DEX treatment transiently increases IOP in mice.

<p>(A) Topical DEX or PBS was administered 3 times a day for 4 to 5 weeks (n = 17–21 for DEX and n = 20–24 for PBS; see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0192665#pone.0192665.t002" target="_blank">Table 2</a>). Graph shows average IOP. IOP of DEX treated eyes is significantly different than PBS treated eyes, *p<0.05. (B) Average weight of mice over the course of treatment. Weight is significantly different than at baseline (BL), *p<0.05. (C) Box and Whisker plot of IOP data from DEX treated mice showing IOP distribution. (D) Box and Whisker plot of IOP data from PBS treated mice showing IOP distribution.