The evolution of the global stellar mass function of star clusters is studied based on a large set of N-body simulations of clusters with a range of initial masses, initial concentrations, in circular or elliptical orbits in different tidal environments. Models with and without initial mass segregation are included. The depletion of low-mass stars in initially Roche-volume (tidal) filling clusters starts typically on a time-scale of the order of the core collapse time. In clusters that are initially underfilling their Roche-volume it takes longer because the clusters have to expand to their tidal radii before dynamical mass-loss becomes important. We introduce the concept of the differential mass function (DMF), which describes the changes ...