Light microscopy images of tubulointerstitial pathology in patients with CKDu in Sri Lanka.

<p>Mild to moderate interstitial fibrosis was found in most patients (black arrow heads in A). Tubular atrophy was mostly mild (black arrows in B). Interstitial inflammation was of varying degree ranging from none to severe (B, A, D and C). Signs of pyelonephritis with interstitial inflammation and neutrophil granulocytes in tubules were found in two patients (white arrow heads in D). [Fig A: Ladewig from Patient 7, bar = 200μm. Fig B: periodic acid Schiff from Patient 4, bar = 100μm. Fig C: hematoxylin-eosin from Patient 3, bar = 100μm. Fig D: hematoxylin-eosin from Patient 11, bar = 100μm.].