MOESM2 of Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases

The Human Melanoma Proteome Atlas-Complementing the melanoma transcriptome

Betancourt, Lazaro Hiram
Gil, Jeovanis
Sanchez, Aniel
Kuras, Magdalena
Velasquez, Erika
Kim, Yonghyo
Sugihara, Yutaka
Parada, Indira Pla
Appelqvist, Roger
Wieslander, Elisabet
Welinder, Charlotte
de Almeida, Natália Pinto
Woldmar, Nicole
Marko-Varga, Matilda
Eriksson, Jonatan
Baldetorp, Bo
Ingvar, Christian
Olsson, Håkan
Lundgren, Lotta
Lindberg, Henrik
Oskolas, Henriett
Lee, Boram
Berge, Ethan
Sjögren, Marie
Eriksson, Carina
Kim, Dasol
Kwon, Ho Jeong
Rezeli, Melinda
Malm, Johan
Horvath, Peter
Horvatovich, Peter
Miliotis, Tasso
Ekedahl, Henrik
Marko-Varga, György
et al.

January 2021

The MM500 meta-study aims to establish a knowledge basis of the tumor proteome to serve as a complem...

Additional file 2: of Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis

Terje Sundstrøm (391510)
Lars Prestegarden (5539034)
Francisco Azuaje (6868)
Synnøve Aasen (6578732)
Gro Røsland (6578735)
Jobin Varughese (6578738)
Marzieh Bahador (6578741)
Simon Bernatz (6578744)
Yannick Braun (6578747)
Patrick Harter (3569069)
Kai Skaftnesmo (6578750)
Elizabeth Ingham (1899424)
Lisa Mahakian (6578753)
Sarah Tam (6578756)
Clifford Tepper (499708)
Kjell Petersen (69736)
Katherine Ferrara (6578759)
Karl Tronstad (6578762)
Morten Lund-Johansen (6578765)
Rudi Beschorner (761326)
Rolf Bjerkvig (68682)
Frits Thorsen (636662)

April 2019

Figure S2. Generation of organ samples for RNA sequencing, brain metastasis gene signature and Conne...

Functional Classification of Cellular Proteome Profiles Support the Identification of Drug Resistance Signatures in Melanoma Cells

Verena Paulitschke
Verena Haudek-prinz
Johannes Griss
Walter Berger
Thomas Mohr
Hubert Pehamberger
Rainer Kunstfeld
Christopher Gerner

August 2016

ABSTRACT: Drug resistance is a major obstacle in melanoma treatment. Recognition of specific resista...

MOESM1 of Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases

Nina Zila (4927534)
Andrea Bileck (817639)
Besnik Muqaku (817637)
Lukas Janker (4927528)
Ossia Eichhoff (4927531)
Phil Cheng (687262)
Reinhard Dummer (103718)
Mitchell Levesque (4861357)
Christopher Gerner (117547)
Verena Paulitschke (134709)

March 2018

Additional file 1: FigureÂ S1. Study outline shows the experimental design of the study

MOESM6 of Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases

Nina Zila (4927534)
Andrea Bileck (817639)
Besnik Muqaku (817637)
Lukas Janker (4927528)
Ossia Eichhoff (4927531)
Phil Cheng (687262)
Reinhard Dummer (103718)
Mitchell Levesque (4861357)
Christopher Gerner (117547)
Verena Paulitschke (134709)

March 2018

Additional file 6: TableÂ S3. Genes upregulated in melanoma cells by TGFÎ˛ signaling correlating wit...

MOESM5 of Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases

Nina Zila (4927534)
Andrea Bileck (817639)
Besnik Muqaku (817637)
Lukas Janker (4927528)
Ossia Eichhoff (4927531)
Phil Cheng (687262)
Reinhard Dummer (103718)
Mitchell Levesque (4861357)
Christopher Gerner (117547)
Verena Paulitschke (134709)

March 2018

Additional file 5: FigureÂ S3. Correlation of proteins (P62937, P61962, Q6FI81, P21266) identified b...

MOESM4 of Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases

Nina Zila (4927534)
Andrea Bileck (817639)
Besnik Muqaku (817637)
Lukas Janker (4927528)
Ossia Eichhoff (4927531)
Phil Cheng (687262)
Reinhard Dummer (103718)
Mitchell Levesque (4861357)
Christopher Gerner (117547)
Verena Paulitschke (134709)

March 2018

Additional file 4: TableÂ S2. Statistical output for GSEA (gene set enrichment analysis). Nominal p-...

Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases

Paulitschke, Verena
Zila, Nina
Bileck, Andrea
Muqaku, Besnik
Janker, Lukas
Eichhoff, Ossia M.
Cheng, Phil F.
Dummer, Reinhard
Levesque, Mitchell P.
Gerner, Christopher

January 2018

Background MAP kinase inhibitor (MAPKi) therapy for BRAF mutated melanoma is characterized by high r...

MOESM2 of The cancer proteomic landscape and the HUPO Cancer Proteome Project

Connie Jimenez (4798938)
Hui Zhang (7197)
Christopher Kinsinger (4798935)
Edouard Nice (460235)

January 2018

Additional file 2: Table S2. Meta-analysis of human cancer genes. Meta-analysis data on driver genes...

MOESM1 of Molecular and epigenetic features of melanomas and tumor immune microenvironment linked to durable remission to ipilimumab-based immunotherapy in metastatic patients

Teofila Seremet (3500810)
Alexander Koch (77280)
Yanina Jansen (3500819)
Max Schreuer (3500825)
Sofie Wilgenhof (3500813)
VĂŠronique Marmol (3500855)
Danielle LiĂ¨nard (3500858)
Kris Thielemans (50626)
Kelly Schats (3500801)
Mark Kockx (3500816)
Wim Criekinge (3500798)
Pierre Coulie (3500807)
Tim Meyer (165859)
Nicolas Baren (3500822)
Bart Neyns (88629)

August 2016

Additional file 1: Table S1. Gene ontology enrichment analysis by GOrilla having for input the compl...

Decoding molecular programs in melanoma brain metastases

Radke, Josefine

August 2022

Supplementary tables associated with the preprint "Decoding molecular programs in melanoma brain met...

Additional file 1: of Deciphering mechanisms of brain metastasis in melanoma - the gist of the matter

Torben Redmer (559735)

July 2018

Table S1. Clinical trials. Results of clinical trials as provided by ( https://www.clinicaltrials.go...

MOESM3 of Open-label, multicenter, single-arm phase II DeCOG-study of ipilimumab in pretreated patients with different subtypes of metastatic melanoma

Lisa Zimmer (486043)
Thomas Eigentler (103619)
Felix Kiecker (72079)
Jan Simon (700889)
Jochen Utikal (524129)
Peter Mohr (103669)
Carola Berking (103608)
Eckhart KĂ¤mpgen (3487541)
Edgar Dippel (3487532)
Rudolf Stadler (3487538)
Axel Hauschild (103637)
Michael Fluck (103622)
Patrick Terheyden (3487529)
Rainer Rompel (700894)
Carmen Loquai (103597)
Zeinab Assi (3487535)
Claus Garbe (48881)
Dirk Schadendorf (103684)

November 2015

Additional file 3: Table S3. Patients with different response pattern in intracranial and extracrani...

MOESM1 of Nanoproteomic analysis of ischemia-dependent changes in signaling protein phosphorylation in colorectal normal and cancer tissue

Florian Unger (2650336)
Nicole Lange (335740)
Jana KrĂźger (3414515)
Carolyn Compton (3414512)
Helen Moore (3414518)
Lokesh Agrawal (3414524)
Hartmut Juhl (506121)
Kerstin David (3414521)

January 2016

Additional file 1: Table S1. Clinical data for the 20 patients analyzed in the study. Presents patie...

MOESM2 of Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors

Michael Gowen (5045855)
Keith Giles (3408602)
Danny Simpson (4397893)
Jeremy Tchack (3455417)
Hua Zhou (50017)
Una Moran (5045852)
Zarmeena Dawood (5045858)
Anna Pavlick (203423)
Shaohui Hu (1917502)
Melissa Wilson (442218)
Hua Zhong (1421908)
Michelle Krogsgaard (242089)
Tomas Kirchhoff (102401)
Iman Osman (37169)

April 2018

Additional file 2: Table S2. Patient characteristics for reproducibility cohort (n = 10). Summary of...

The Human Melanoma Proteome Atlas-Complementing the melanoma transcriptome

Betancourt, Lazaro Hiram
Gil, Jeovanis
Sanchez, Aniel
Kuras, Magdalena
Velasquez, Erika
Kim, Yonghyo
Sugihara, Yutaka
Parada, Indira Pla
Appelqvist, Roger
Wieslander, Elisabet
Welinder, Charlotte
de Almeida, Natália Pinto
Woldmar, Nicole
Marko-Varga, Matilda
Eriksson, Jonatan
Baldetorp, Bo
Ingvar, Christian
Olsson, Håkan
Lundgren, Lotta
Lindberg, Henrik
Oskolas, Henriett
Lee, Boram
Berge, Ethan
Sjögren, Marie
Eriksson, Carina
Kim, Dasol
Kwon, Ho Jeong
Rezeli, Melinda
Malm, Johan
Horvath, Peter
Horvatovich, Peter
Miliotis, Tasso
Ekedahl, Henrik
Marko-Varga, György
et al.

January 2021

The MM500 meta-study aims to establish a knowledge basis of the tumor proteome to serve as a complem...

Additional file 2: of Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis

Terje Sundstrøm (391510)
Lars Prestegarden (5539034)
Francisco Azuaje (6868)
Synnøve Aasen (6578732)
Gro Røsland (6578735)
Jobin Varughese (6578738)
Marzieh Bahador (6578741)
Simon Bernatz (6578744)
Yannick Braun (6578747)
Patrick Harter (3569069)
Kai Skaftnesmo (6578750)
Elizabeth Ingham (1899424)
Lisa Mahakian (6578753)
Sarah Tam (6578756)
Clifford Tepper (499708)
Kjell Petersen (69736)
Katherine Ferrara (6578759)
Karl Tronstad (6578762)
Morten Lund-Johansen (6578765)
Rudi Beschorner (761326)
Rolf Bjerkvig (68682)
Frits Thorsen (636662)

April 2019

Figure S2. Generation of organ samples for RNA sequencing, brain metastasis gene signature and Conne...

Functional Classification of Cellular Proteome Profiles Support the Identification of Drug Resistance Signatures in Melanoma Cells

Verena Paulitschke
Verena Haudek-prinz
Johannes Griss
Walter Berger
Thomas Mohr
Hubert Pehamberger
Rainer Kunstfeld
Christopher Gerner

August 2016

ABSTRACT: Drug resistance is a major obstacle in melanoma treatment. Recognition of specific resista...

MOESM1 of Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases

Nina Zila (4927534)
Andrea Bileck (817639)
Besnik Muqaku (817637)
Lukas Janker (4927528)
Ossia Eichhoff (4927531)
Phil Cheng (687262)
Reinhard Dummer (103718)
Mitchell Levesque (4861357)
Christopher Gerner (117547)
Verena Paulitschke (134709)

March 2018

Additional file 1: FigureÂ S1. Study outline shows the experimental design of the study

MOESM6 of Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases

Nina Zila (4927534)
Andrea Bileck (817639)
Besnik Muqaku (817637)
Lukas Janker (4927528)
Ossia Eichhoff (4927531)
Phil Cheng (687262)
Reinhard Dummer (103718)
Mitchell Levesque (4861357)
Christopher Gerner (117547)
Verena Paulitschke (134709)

March 2018

Additional file 6: TableÂ S3. Genes upregulated in melanoma cells by TGFÎ˛ signaling correlating wit...

MOESM5 of Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases

Nina Zila (4927534)
Andrea Bileck (817639)
Besnik Muqaku (817637)
Lukas Janker (4927528)
Ossia Eichhoff (4927531)
Phil Cheng (687262)
Reinhard Dummer (103718)
Mitchell Levesque (4861357)
Christopher Gerner (117547)
Verena Paulitschke (134709)

March 2018

Additional file 5: FigureÂ S3. Correlation of proteins (P62937, P61962, Q6FI81, P21266) identified b...

MOESM4 of Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases

Nina Zila (4927534)
Andrea Bileck (817639)
Besnik Muqaku (817637)
Lukas Janker (4927528)
Ossia Eichhoff (4927531)
Phil Cheng (687262)
Reinhard Dummer (103718)
Mitchell Levesque (4861357)
Christopher Gerner (117547)
Verena Paulitschke (134709)

March 2018

Additional file 4: TableÂ S2. Statistical output for GSEA (gene set enrichment analysis). Nominal p-...

Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases

Paulitschke, Verena
Zila, Nina
Bileck, Andrea
Muqaku, Besnik
Janker, Lukas
Eichhoff, Ossia M.
Cheng, Phil F.
Dummer, Reinhard
Levesque, Mitchell P.
Gerner, Christopher

January 2018

Background MAP kinase inhibitor (MAPKi) therapy for BRAF mutated melanoma is characterized by high r...

MOESM2 of The cancer proteomic landscape and the HUPO Cancer Proteome Project

Connie Jimenez (4798938)
Hui Zhang (7197)
Christopher Kinsinger (4798935)
Edouard Nice (460235)

January 2018

Additional file 2: Table S2. Meta-analysis of human cancer genes. Meta-analysis data on driver genes...

MOESM1 of Molecular and epigenetic features of melanomas and tumor immune microenvironment linked to durable remission to ipilimumab-based immunotherapy in metastatic patients

Teofila Seremet (3500810)
Alexander Koch (77280)
Yanina Jansen (3500819)
Max Schreuer (3500825)
Sofie Wilgenhof (3500813)
VĂŠronique Marmol (3500855)
Danielle LiĂ¨nard (3500858)
Kris Thielemans (50626)
Kelly Schats (3500801)
Mark Kockx (3500816)
Wim Criekinge (3500798)
Pierre Coulie (3500807)
Tim Meyer (165859)
Nicolas Baren (3500822)
Bart Neyns (88629)

August 2016

Additional file 1: Table S1. Gene ontology enrichment analysis by GOrilla having for input the compl...

Decoding molecular programs in melanoma brain metastases

Radke, Josefine

August 2022

Supplementary tables associated with the preprint "Decoding molecular programs in melanoma brain met...

Additional file 1: of Deciphering mechanisms of brain metastasis in melanoma - the gist of the matter

Torben Redmer (559735)

July 2018

Table S1. Clinical trials. Results of clinical trials as provided by ( https://www.clinicaltrials.go...

MOESM3 of Open-label, multicenter, single-arm phase II DeCOG-study of ipilimumab in pretreated patients with different subtypes of metastatic melanoma

Lisa Zimmer (486043)
Thomas Eigentler (103619)
Felix Kiecker (72079)
Jan Simon (700889)
Jochen Utikal (524129)
Peter Mohr (103669)
Carola Berking (103608)
Eckhart KĂ¤mpgen (3487541)
Edgar Dippel (3487532)
Rudolf Stadler (3487538)
Axel Hauschild (103637)
Michael Fluck (103622)
Patrick Terheyden (3487529)
Rainer Rompel (700894)
Carmen Loquai (103597)
Zeinab Assi (3487535)
Claus Garbe (48881)
Dirk Schadendorf (103684)

November 2015

Additional file 3: Table S3. Patients with different response pattern in intracranial and extracrani...

MOESM1 of Nanoproteomic analysis of ischemia-dependent changes in signaling protein phosphorylation in colorectal normal and cancer tissue

Florian Unger (2650336)
Nicole Lange (335740)
Jana KrĂźger (3414515)
Carolyn Compton (3414512)
Helen Moore (3414518)
Lokesh Agrawal (3414524)
Hartmut Juhl (506121)
Kerstin David (3414521)

January 2016

Additional file 1: Table S1. Clinical data for the 20 patients analyzed in the study. Presents patie...

MOESM2 of Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors

Michael Gowen (5045855)
Keith Giles (3408602)
Danny Simpson (4397893)
Jeremy Tchack (3455417)
Hua Zhou (50017)
Una Moran (5045852)
Zarmeena Dawood (5045858)
Anna Pavlick (203423)
Shaohui Hu (1917502)
Melissa Wilson (442218)
Hua Zhong (1421908)
Michelle Krogsgaard (242089)
Tomas Kirchhoff (102401)
Iman Osman (37169)

April 2018

Additional file 2: Table S2. Patient characteristics for reproducibility cohort (n = 10). Summary of...

The Human Melanoma Proteome Atlas-Complementing the melanoma transcriptome

Betancourt, Lazaro Hiram
Gil, Jeovanis
Sanchez, Aniel
Kuras, Magdalena
Velasquez, Erika
Kim, Yonghyo
Sugihara, Yutaka
Parada, Indira Pla
Appelqvist, Roger
Wieslander, Elisabet
Welinder, Charlotte
de Almeida, Natália Pinto
Woldmar, Nicole
Marko-Varga, Matilda
Eriksson, Jonatan
Baldetorp, Bo
Ingvar, Christian
Olsson, Håkan
Lundgren, Lotta
Lindberg, Henrik
Oskolas, Henriett
Lee, Boram
Berge, Ethan
Sjögren, Marie
Eriksson, Carina
Kim, Dasol
Kwon, Ho Jeong
Rezeli, Melinda
Malm, Johan
Horvath, Peter
Horvatovich, Peter
Miliotis, Tasso
Ekedahl, Henrik
Marko-Varga, György
et al.

January 2021

The MM500 meta-study aims to establish a knowledge basis of the tumor proteome to serve as a complem...

Additional file 2: of Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis

Terje Sundstrøm (391510)
Lars Prestegarden (5539034)
Francisco Azuaje (6868)
Synnøve Aasen (6578732)
Gro Røsland (6578735)
Jobin Varughese (6578738)
Marzieh Bahador (6578741)
Simon Bernatz (6578744)
Yannick Braun (6578747)
Patrick Harter (3569069)
Kai Skaftnesmo (6578750)
Elizabeth Ingham (1899424)
Lisa Mahakian (6578753)
Sarah Tam (6578756)
Clifford Tepper (499708)
Kjell Petersen (69736)
Katherine Ferrara (6578759)
Karl Tronstad (6578762)
Morten Lund-Johansen (6578765)
Rudi Beschorner (761326)
Rolf Bjerkvig (68682)
Frits Thorsen (636662)

April 2019

Figure S2. Generation of organ samples for RNA sequencing, brain metastasis gene signature and Conne...

Functional Classification of Cellular Proteome Profiles Support the Identification of Drug Resistance Signatures in Melanoma Cells

Verena Paulitschke
Verena Haudek-prinz
Johannes Griss
Walter Berger
Thomas Mohr
Hubert Pehamberger
Rainer Kunstfeld
Christopher Gerner

August 2016

ABSTRACT: Drug resistance is a major obstacle in melanoma treatment. Recognition of specific resista...

MOESM2 of Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases

Abstract

Extracted data

MOESM2 of Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases

Abstract

Extracted data

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