Mutation pattern in ERBB receptor family.
- Ulrika A. Hänninen (4925722)
- Riku Katainen (473503)
- Tomas Tanskanen (473505)
- Roosa-Maria Plaketti (4925728)
- Riku Laine (4925725)
- Jiri Hamberg (4925713)
- Ari Ristimäki (95126)
- Eero Pukkala (27299)
- Minna Taipale (473508)
- Jukka-Pekka Mecklin (27351)
- Linda M. Forsström (4925716)
- Esa Pitkänen (277010)
- Kimmo Palin (4925719)
- Niko Välimäki (800617)
- Netta Mäkinen (2147074)
- Lauri A. Aaltonen (218872)
Publication date
March 2018
DOIAbstract
<p>Mutations in <i>ERBB2</i> (ENST00000269571) grouped into four hotspots (top). Samples (n = 29) with a mutated member of ERBB receptor family are presented in columns (below). In addition to a hotspot mutation, some samples displayed simultaneously a non-hotspot mutation in the same gene, thus all mutations are not shown in the figure. Recep_L = Receptor L domain; Furin-like = Furin-like cysteine rich region; GF_recep = Growth factor receptor domain; Pkinase_Tyr = Protein tyrosine kinase.</p
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