Analysis of early steady state to late steady state fitness changes.

<p>(<b>A</b>) Comparison of fitness between the early steady state (ESS) and late steady state (LSS) stages under the three indicated carbon-limited conditions. Haplo-proficient deletion strains have positive Log2 fold change and haplo-insufficient deletion strains have negative Log2 fold change. (<b>B</b>) Comparison of fitness between the early steady state (ESS) and late steady state (LSS) stages under the three indicated nitrogen-limited conditions. Haplo-proficient deletion strains have positive Log2 fold change and haplo-insufficient deletion strains have negative Log2 fold change. Any strains falling outside the grey shaded area have a significant fitness difference (p < 0.05). Graphs where individual points can be identified are found in <b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1007253#pgen.1007253.s004" target="_blank">S4</a>–<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1007253#pgen.1007253.s009" target="_blank">S9</a> Tables</b>.