Background: Alcoholism, a chronic behavioral disorder characterized by excessive alcohol consumption, has been a leading cause of morbidity and premature death. This condition is believed to be influenced by genetic factors. As copy number variation (CNV) has been recently discovered in human genome, genomic diversity of human genome is more frequent than previously thought. Many studies have reported evidences that CNV is associated with the development of complex diseases. In this study, we hypothesized that CNV can predict the risk of alcoholism.Methods: Using the Illumina HumanHap660W-Quad BeadChip (similar to 660 k markers), genome-wide genotyping was performed to obtain signal and allelic intensities from 116 alcoholic cases and 1,022...
BackgroundDespite the high heritability of alcohol dependence (AD), the genes found to be associated...
Genome-wide association studies (GWAS) of alcohol dependence (AD) have reliably identified variation...
Background: The organization of risk genes within signaling pathways may provide clues about the con...
Background:  Alcoholism, a chronic behavioral disorder characterized by excessive alcohol consu...
Background: Excessive alcohol use is the third leading cause of preventable death and is highly corr...
Background and aims: The quantity of alcohol leading to alcohol-associated liver disease (ALD) varie...
Aims: Alcohol problems (AP) contribute substantially to the global disease burden. Twin and family s...
Alcohol consumption can increase the risk of chronic diseases, such as myocardial infarction, corona...
Alcoholism is an urgent public health issue concerning certain populations who may be at greater ris...
AIMS: The study aimed to identify specific genes and functional genetic variants affecting susceptib...
Alcohol metabolism is one of the biological determinants that could significantly be influenced by g...
Problematic alcohol use (PAU) is a leading cause of death and disability worldwide. Although genome-...
The susceptibility to developing alcohol dependence and significant alcohol-related liver injury is ...
Background: Unlike Caucasian populations, genetic factors contributing to the risk of type 2 diabete...
We have used a translational Convergent Functional Genomics (CFG) approach to discover genes involve...
BackgroundDespite the high heritability of alcohol dependence (AD), the genes found to be associated...
Genome-wide association studies (GWAS) of alcohol dependence (AD) have reliably identified variation...
Background: The organization of risk genes within signaling pathways may provide clues about the con...
Background:  Alcoholism, a chronic behavioral disorder characterized by excessive alcohol consu...
Background: Excessive alcohol use is the third leading cause of preventable death and is highly corr...
Background and aims: The quantity of alcohol leading to alcohol-associated liver disease (ALD) varie...
Aims: Alcohol problems (AP) contribute substantially to the global disease burden. Twin and family s...
Alcohol consumption can increase the risk of chronic diseases, such as myocardial infarction, corona...
Alcoholism is an urgent public health issue concerning certain populations who may be at greater ris...
AIMS: The study aimed to identify specific genes and functional genetic variants affecting susceptib...
Alcohol metabolism is one of the biological determinants that could significantly be influenced by g...
Problematic alcohol use (PAU) is a leading cause of death and disability worldwide. Although genome-...
The susceptibility to developing alcohol dependence and significant alcohol-related liver injury is ...
Background: Unlike Caucasian populations, genetic factors contributing to the risk of type 2 diabete...
We have used a translational Convergent Functional Genomics (CFG) approach to discover genes involve...
BackgroundDespite the high heritability of alcohol dependence (AD), the genes found to be associated...
Genome-wide association studies (GWAS) of alcohol dependence (AD) have reliably identified variation...
Background: The organization of risk genes within signaling pathways may provide clues about the con...