In vitro anti-bacterial activity of titanium oxide nano-composites containing benzalkonium chloride and chlorhexidine gluconate

Thesis (MTech (Biomedical Technology))--Cape Peninsula University of Technology, 2013.Newly developed and commercial dental resins which are commonly used nowadays have to be tested for their antimicrobial susceptibility. The purpose of this in vitro study was to investigate the antimicrobial activity of a titanium oxide (Ti02) nano-composite which was prepared with different antibacterial substances and used as restoratives in dentistry to combat certain selected bacteria that are considered the principle causes of some tooth diseases, for example, tooth decay and to prevent unsuccessful dental restoration. The Ti02 nano-composite was prepared and divided into four groups: The first group was an untreated Ti02 nano-composite. The second group was silane-treated Ti02 nano-composite. The third group was treated Ti02 nano-composite which was combined with chlorhexidine gluconate (CHxG). The fourth group was treated Ti02 nano-composite which was combined with benzalkonium chloride (BzCI)