Hypoxia is a condition of inadequate oxygen supply, which can induce cell death. Using human neuronal cells treated with a hypoxia memetic compound, desferoxamine (DFO), a hypoxic cell model system was created. Our lab reported previously that treatment with DFO resulted in the decrease of cell viability. However, there were still surviving neurons. The surviving cells did not exhibit significant morphological changes, as compared to the control cells, under confocal microscopy analysis using annexin-V-FLUOS and propidium iodide staining, indicating that they were not at apoptotic or necrotic stages. These surviving neurons, therefore, developed adaptive responses under hypoxic challenge. Several changes were observed, including an increase...
Hypoxia has been implicated in nerve cell deaths in many neurological disorders and opioid receptor ...
Hypoxia has been implicated in nerve cell deaths in many neurological disorders and opioid receptor ...
Oxidative stress adversely affects neuronal cells in which they may die when oxygen supply is reduce...
Hypoxia is a condition of inadequate oxygen supply, which can induce cell death. Using human neurona...
Hypoxia is a condition of inadequate oxygen supply, which can induce cell death. Using human neurona...
Hypoxia is a condition of inadequate oxygen supply, which can induce cell death. Using human neurona...
Hypoxia is a condition of inadequate oxygen supply, which can induce cell death. Using human neurona...
Previously, our laboratory used desferoxamine (DFO), to generate hypoxic conditions (a low oxygen co...
Cellular adaptation to hypoxia is a protective mechanism for neurons and relevant to cancer. Treatme...
Previously, our laboratory used desferoxamine (DFO), to generate hypoxic conditions (a low oxygen co...
Cellular adaptation to hypoxia is a protective mechanism for neurons and relevant to cancer. Treatme...
While diseases such as cancer and diabetes, or surgery and traumatic injury can cause hypoxia throug...
Hypoxia adversely affects cells and tissues, and neuronal cells in particular have been shown to be ...
Introduction: Hypoxia has been implicated in nerve cell deaths that occur in a variety of neurologic...
Introduction: Hypoxia has been implicated in nerve cell deaths that occur in a variety of neurologic...
Hypoxia has been implicated in nerve cell deaths in many neurological disorders and opioid receptor ...
Hypoxia has been implicated in nerve cell deaths in many neurological disorders and opioid receptor ...
Oxidative stress adversely affects neuronal cells in which they may die when oxygen supply is reduce...
Hypoxia is a condition of inadequate oxygen supply, which can induce cell death. Using human neurona...
Hypoxia is a condition of inadequate oxygen supply, which can induce cell death. Using human neurona...
Hypoxia is a condition of inadequate oxygen supply, which can induce cell death. Using human neurona...
Hypoxia is a condition of inadequate oxygen supply, which can induce cell death. Using human neurona...
Previously, our laboratory used desferoxamine (DFO), to generate hypoxic conditions (a low oxygen co...
Cellular adaptation to hypoxia is a protective mechanism for neurons and relevant to cancer. Treatme...
Previously, our laboratory used desferoxamine (DFO), to generate hypoxic conditions (a low oxygen co...
Cellular adaptation to hypoxia is a protective mechanism for neurons and relevant to cancer. Treatme...
While diseases such as cancer and diabetes, or surgery and traumatic injury can cause hypoxia throug...
Hypoxia adversely affects cells and tissues, and neuronal cells in particular have been shown to be ...
Introduction: Hypoxia has been implicated in nerve cell deaths that occur in a variety of neurologic...
Introduction: Hypoxia has been implicated in nerve cell deaths that occur in a variety of neurologic...
Hypoxia has been implicated in nerve cell deaths in many neurological disorders and opioid receptor ...
Hypoxia has been implicated in nerve cell deaths in many neurological disorders and opioid receptor ...
Oxidative stress adversely affects neuronal cells in which they may die when oxygen supply is reduce...