Number of computational tools of mathematical models allow simulations of performance and analysis of the established models of biological systems in the field of synthetic and systems biology are already in place. The biggest drawback of the existing tools is the lack of modularity. The main objective of the thesis is to develop a modular framework that will enable development and integration of various building blocks mainly for synthetic and systems biology, and to enable future users and researchers to easily add their own modules that implement modern approaches to modeling, analysis and design of biological systems. This paper introduces methods, tools, and development itself for establishing such a modular system, as well as instruct...
Motivation: Fabrication of synthetic biological systems is greatly enhanced by incorporating enginee...
Systems Biology studies the relationships and interactions between parts of biological systems (such...
International audienceMechanistic computational models enable the study of regulatory mechanisms imp...
Systems biology is a rapidly growing field which seeks a refined quantitative understanding of organ...
Biological researchers increasingly rely on computational models to integrate biological systems kno...
Synthetic Biology is characterized by a forward engineering approach to the design of biological sys...
Mathematical models are increasingly used to understand how phenotypes emerge from systems of molecu...
Motivation: Need for software to setup and analyze complex mathematical models for cellular systems ...
Modelling and computational simulation are crucial for the large-scale engineering of biological cir...
Modelling and computational simulation are crucial for the large-scale engineering of biological cir...
Abstract Motivation: Modeling of complex biological systems such as cells, organs or even whole or...
There is a growing awareness for the need to understand the basic design principles of living system...
Modelling and computational simulation are crucial for the large-scale engineering of biological cir...
In this paper we propose an extension of a systems/synthetic biology modelling framework based on P ...
International audienceOne of the most ambitious goals in biological engineering is the ability to co...
Motivation: Fabrication of synthetic biological systems is greatly enhanced by incorporating enginee...
Systems Biology studies the relationships and interactions between parts of biological systems (such...
International audienceMechanistic computational models enable the study of regulatory mechanisms imp...
Systems biology is a rapidly growing field which seeks a refined quantitative understanding of organ...
Biological researchers increasingly rely on computational models to integrate biological systems kno...
Synthetic Biology is characterized by a forward engineering approach to the design of biological sys...
Mathematical models are increasingly used to understand how phenotypes emerge from systems of molecu...
Motivation: Need for software to setup and analyze complex mathematical models for cellular systems ...
Modelling and computational simulation are crucial for the large-scale engineering of biological cir...
Modelling and computational simulation are crucial for the large-scale engineering of biological cir...
Abstract Motivation: Modeling of complex biological systems such as cells, organs or even whole or...
There is a growing awareness for the need to understand the basic design principles of living system...
Modelling and computational simulation are crucial for the large-scale engineering of biological cir...
In this paper we propose an extension of a systems/synthetic biology modelling framework based on P ...
International audienceOne of the most ambitious goals in biological engineering is the ability to co...
Motivation: Fabrication of synthetic biological systems is greatly enhanced by incorporating enginee...
Systems Biology studies the relationships and interactions between parts of biological systems (such...
International audienceMechanistic computational models enable the study of regulatory mechanisms imp...