Francisella tularensis, the etiologic agent of tularemia and a Class A Select Agent, is divided into three subspecies and multiple subpopulations that differ in virulence and geographic distribution. Given these differences, there is a need to rapidly and accurately determine if a strain is F. tularensis and, if it is, assign it to subspecies and subpopulation. We designed TaqMan real-time PCR genotyping assays using eleven single nucleotide polymorphisms (SNPs) that were potentially specific to closely related groups within the genus Francisella, including numerous subpopulations within F. tularensis species. We performed extensive validation studies to test the specificity of these SNPs to particular populations by screening the assays ac...
Tularemia is a geographically widespread, severely debilitating, and occasionally lethal disease in ...
In this study, we evaluated three PCR methods for epidemiological typing of Francisella tularensis: ...
Following detection of putative Francisella species in aerosol samples from Houston, Texas, we surve...
Francisella tularensis, the etiologic agent of tularemia and a Class A Select Agent, is divided into...
<div><p><i>Francisella tularensis</i>, the etiologic agent of tularemia and a Class A Select Agent, ...
Francisella tularensis, the etiologic agent of tularemia and a Class A Select Agent, is divided into...
A PCR assay was developed to genotypically characterize Francisella tularensis and F. novicida. An i...
Francisella tularensis, the etiological agent of tularemia, is found throughout the Northern hemisph...
In recent years, an increasing diversity of species has been recognized within the family Francisell...
Francisella tularensis subsp. tularensis (type A) is subdivided into clades A1 and A2. Human tularem...
A robust, rapid and flexible real-time PCR assay for hierarchical genetic typing of clinical and env...
Abstract Background A low genetic diversity in Francisella tularensis has been documented. Current D...
Tularemia, caused by the Gram-negative bacterium Francisella tularensis, is a life-threatening human...
Francisella tularensis, the bacterium that causes the zoonosis tularemia, and its genetic near neigh...
Francisella tularensis is a potent pathogen and a possible bioterrorism agent. Little is known, howe...
Tularemia is a geographically widespread, severely debilitating, and occasionally lethal disease in ...
In this study, we evaluated three PCR methods for epidemiological typing of Francisella tularensis: ...
Following detection of putative Francisella species in aerosol samples from Houston, Texas, we surve...
Francisella tularensis, the etiologic agent of tularemia and a Class A Select Agent, is divided into...
<div><p><i>Francisella tularensis</i>, the etiologic agent of tularemia and a Class A Select Agent, ...
Francisella tularensis, the etiologic agent of tularemia and a Class A Select Agent, is divided into...
A PCR assay was developed to genotypically characterize Francisella tularensis and F. novicida. An i...
Francisella tularensis, the etiological agent of tularemia, is found throughout the Northern hemisph...
In recent years, an increasing diversity of species has been recognized within the family Francisell...
Francisella tularensis subsp. tularensis (type A) is subdivided into clades A1 and A2. Human tularem...
A robust, rapid and flexible real-time PCR assay for hierarchical genetic typing of clinical and env...
Abstract Background A low genetic diversity in Francisella tularensis has been documented. Current D...
Tularemia, caused by the Gram-negative bacterium Francisella tularensis, is a life-threatening human...
Francisella tularensis, the bacterium that causes the zoonosis tularemia, and its genetic near neigh...
Francisella tularensis is a potent pathogen and a possible bioterrorism agent. Little is known, howe...
Tularemia is a geographically widespread, severely debilitating, and occasionally lethal disease in ...
In this study, we evaluated three PCR methods for epidemiological typing of Francisella tularensis: ...
Following detection of putative Francisella species in aerosol samples from Houston, Texas, we surve...