This thesis describes how transmission of the 2009 A/H1N1 influenza pandemic in the United States varied geographically, with emphasis on population distribution and age structure. This is made possible by the availability of medical claims records maintained in the private sector that capture the weekly incidence of influenza-like illness in 834 US cities. First, a probabilistic method is developed to infer each city's outbreak onset time. This reveals a clear wave-like pattern of transmission originating in the south-eastern US. Then, a mechanistic mathematical model is constructed to describe the between-city transmission of the epidemic. A model selection procedure reveals that transmission to a city is modulated by its population size...
Background: Confirmed H1N1 cases during late spring and summer 2009 in various countries showed a su...
Background: Understanding the mechanism of influenza spread across multiple geographic scales is not...
Infecting large portions of the global population, seasonal influenza is a major burden on societies...
A key issue in infectious disease epidemiology is to identify and predict geographic sites of epidem...
The 2009 H1N1 influenza pandemic provides a unique opportunity for detailed examination of the spati...
The 2009 H1N1 influenza pandemic provides a unique opportunity for detailed examination of the spati...
Spatial variation in the epidemiological patterns of successive waves of pandemic influenza virus in...
In this paper, the authors develop a method of detecting correlations between epidemic patterns in d...
New strains of influenza spread around the globe via the movement of infected individuals. The globa...
<div><p>Seasonal influenza epidemics offer unique opportunities to study the invasion and re-invasio...
International audienceBACKGROUND: Confirmed H1N1 cases during late spring and summer 2009 in various...
The inference of key infectious disease epidemiological parameters is critical for characterizing di...
The 1918 influenza pandemic was one of the most devastating and enigmatic infectious disease outbrea...
BACKGROUND: Influenza is a contagious respiratory disease responsible for annual seasonal epidemics ...
BACKGROUND: Understanding the mechanism of influenza spread across multiple geographic scales is not...
Background: Confirmed H1N1 cases during late spring and summer 2009 in various countries showed a su...
Background: Understanding the mechanism of influenza spread across multiple geographic scales is not...
Infecting large portions of the global population, seasonal influenza is a major burden on societies...
A key issue in infectious disease epidemiology is to identify and predict geographic sites of epidem...
The 2009 H1N1 influenza pandemic provides a unique opportunity for detailed examination of the spati...
The 2009 H1N1 influenza pandemic provides a unique opportunity for detailed examination of the spati...
Spatial variation in the epidemiological patterns of successive waves of pandemic influenza virus in...
In this paper, the authors develop a method of detecting correlations between epidemic patterns in d...
New strains of influenza spread around the globe via the movement of infected individuals. The globa...
<div><p>Seasonal influenza epidemics offer unique opportunities to study the invasion and re-invasio...
International audienceBACKGROUND: Confirmed H1N1 cases during late spring and summer 2009 in various...
The inference of key infectious disease epidemiological parameters is critical for characterizing di...
The 1918 influenza pandemic was one of the most devastating and enigmatic infectious disease outbrea...
BACKGROUND: Influenza is a contagious respiratory disease responsible for annual seasonal epidemics ...
BACKGROUND: Understanding the mechanism of influenza spread across multiple geographic scales is not...
Background: Confirmed H1N1 cases during late spring and summer 2009 in various countries showed a su...
Background: Understanding the mechanism of influenza spread across multiple geographic scales is not...
Infecting large portions of the global population, seasonal influenza is a major burden on societies...