Histone deacetylase inhibitors and periodontal bone loss
- Cantley, M. D.
- Bartold, P. M.
- Marino, V.
- Fairlie, D. P.
- Le, G. T.
- Lucke, A. J.
- Haynes, D. R.
Publication date
December 2011
DOI Publisher
Wiley ISSN
0022-3484 Citation count (estimate)
27Abstract
Background and Objective: Bone loss caused by enhanced osteoclast activity is a significant feature of periodontitis. Histone deacetylase inhibitors (HDACi) can suppress osteoclast-mediated bone loss in vitro and in vivo. This study investigated whether HDACi can suppress bone loss in experimental periodontitis
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