C15 disease-modifying antirheumatic drugs

RHEUMATOID ARTHRITIS (RA) is the most common inflammatory rheumatic disease, with a prevalence of about 1%. Targeting the synovial membrane, cartilage and bone, untreated RA leads to joint destruction, disability and increased mortality. Although the total incidence of this disease is low, the level of ill health and economic burden is significant with the patients often partially or totally unemployed. Generally, the patients require long-term drug treatment and non-pharmacological approaches such as physiotherapy and psychosocial support