cited By 229International audienceOxidation of methionine residues to methionine sulfoxide can lead to inactivation of proteins. Methionine sulfoxide reductase (MsrA) has been known for a long time, and its repairing function well characterized. Here we identify a new methionine sulfoxide reductase, which we referred to as MsrB, the gene of which is present in genomes of eubacteria, archaebacteria, and eucaryotes. The msrA and msrB genes exhibit no sequence similarity and, in some genomes, are fused. The Escherichia coli MsrB protein (currently predicted to be encoded by an open reading frame of unknown function named yeaA) was used for genetic, enzymatic, and mass spectrometric investigations. Our in vivo study revealed that msrB is requir...
Methionine sulfoxide reductases, enzymes that reverse the oxidation of methionine residues, have bee...
Proteins are subject to modification by reactive oxygen species (ROS), and oxidation of specific ami...
The oxidation of free and protein-bound methionine into methionine sulfoxide is a frequently occurri...
cited By 229International audienceOxidation of methionine residues to methionine sulfoxide can lead ...
Oxidation of methionine residues to methionine sulfoxide can lead to inactivation of proteins. Methi...
The reactive species of oxygen (ROS) and chlorine (RCS) damage cellular components, potentially lead...
International audienceIn proteins, methionine (Met) can be oxidized into Met sulfoxide (MetO). The u...
International audienceThe reactive species of oxygen and chlorine damage cellular components, potent...
The sulfur-containing amino acid methionine (Met) in its free and amino acid residue forms can be re...
International audienceThe oxidation of free methionine (Met) and Met residues inside proteins leads ...
International audienceMethionine, either as a free amino acid or included in proteins, can be oxidiz...
ABSTRACT Methionine sulfoxide reductase A (MsrA) is an antioxidant enzyme found in all domains of li...
Sulfoxides occur in biology as products of the S-oxygenation of small molecules as well as in peptid...
Methionine sulfoxide reductases, enzymes that reverse the oxidation of methionine residues, have bee...
Proteins are subject to modification by reactive oxygen species (ROS), and oxidation of specific ami...
The oxidation of free and protein-bound methionine into methionine sulfoxide is a frequently occurri...
cited By 229International audienceOxidation of methionine residues to methionine sulfoxide can lead ...
Oxidation of methionine residues to methionine sulfoxide can lead to inactivation of proteins. Methi...
The reactive species of oxygen (ROS) and chlorine (RCS) damage cellular components, potentially lead...
International audienceIn proteins, methionine (Met) can be oxidized into Met sulfoxide (MetO). The u...
International audienceThe reactive species of oxygen and chlorine damage cellular components, potent...
The sulfur-containing amino acid methionine (Met) in its free and amino acid residue forms can be re...
International audienceThe oxidation of free methionine (Met) and Met residues inside proteins leads ...
International audienceMethionine, either as a free amino acid or included in proteins, can be oxidiz...
ABSTRACT Methionine sulfoxide reductase A (MsrA) is an antioxidant enzyme found in all domains of li...
Sulfoxides occur in biology as products of the S-oxygenation of small molecules as well as in peptid...
Methionine sulfoxide reductases, enzymes that reverse the oxidation of methionine residues, have bee...
Proteins are subject to modification by reactive oxygen species (ROS), and oxidation of specific ami...
The oxidation of free and protein-bound methionine into methionine sulfoxide is a frequently occurri...