This is the final version of the article. Available from Springer via the DOI in this record.An erratum to this article is available at http://dx.doi.org/10.1007/s00285-016-1044-y and in ORE at http://hdl.handle.net/10871/31444Variable-Internal-Stores models of microbial metabolism and growth have proven to be invaluable in accounting for changes in cellular composition as microbial cells adapt to varying conditions of nutrient availability. Here, such a model is extended with explicit allocation of molecular building blocks among various types of catalytic machinery. Such an extension allows a reconstruction of the regulatory rules employed by the cell as it adapts its physiology to changing environmental conditions. Moreover, the extensio...
Exposed to changes in their environment, microorganisms will adapt their phenotype, including metabo...
International audienceIntracellular processes rarely work in isolation but continually interact with...
In simple organisms like E.coli, the metabolic response to an external perturbation passes through a...
Variable-Internal-Stores models of microbial metabolism and growth have proven to be invaluable in a...
This is the final version of the article. Available from Springer via the DOI in this record. The...
This is the author accepted manuscript. The final version is available from Science Reviews 2000 via...
We review the principles underpinning the development of mathematical models of the metabolic activi...
Intracellular reserves are a conspicuous feature of many bacteria; such internal stores are often pr...
This thesis presents the development and analysis of a macro-chemical kinetics model of microbial me...
We consider a model of bacterial growth with variable internal stores, extended with adaptive resour...
Background The rising consensus that the cell can dynamically allocate its resources provides an int...
Microbial cells evolved a remarkable ability to adapt to environmental conditions, or to withstand o...
Corynebacterium glutamicum serves as important production host for small molecular compounds that ar...
Abstract Genome-scale stoichiometric models, con-strained to optimise biomass production are often u...
The study of bacterial growth has highlighted the importance of metabolism in how microorganisms hav...
Exposed to changes in their environment, microorganisms will adapt their phenotype, including metabo...
International audienceIntracellular processes rarely work in isolation but continually interact with...
In simple organisms like E.coli, the metabolic response to an external perturbation passes through a...
Variable-Internal-Stores models of microbial metabolism and growth have proven to be invaluable in a...
This is the final version of the article. Available from Springer via the DOI in this record. The...
This is the author accepted manuscript. The final version is available from Science Reviews 2000 via...
We review the principles underpinning the development of mathematical models of the metabolic activi...
Intracellular reserves are a conspicuous feature of many bacteria; such internal stores are often pr...
This thesis presents the development and analysis of a macro-chemical kinetics model of microbial me...
We consider a model of bacterial growth with variable internal stores, extended with adaptive resour...
Background The rising consensus that the cell can dynamically allocate its resources provides an int...
Microbial cells evolved a remarkable ability to adapt to environmental conditions, or to withstand o...
Corynebacterium glutamicum serves as important production host for small molecular compounds that ar...
Abstract Genome-scale stoichiometric models, con-strained to optimise biomass production are often u...
The study of bacterial growth has highlighted the importance of metabolism in how microorganisms hav...
Exposed to changes in their environment, microorganisms will adapt their phenotype, including metabo...
International audienceIntracellular processes rarely work in isolation but continually interact with...
In simple organisms like E.coli, the metabolic response to an external perturbation passes through a...