Contemporary naturalism is changing and scientific reductionism is under challenge from those who advocate a more comprehensive outlook. This special issue of Telos, based on the first Telos Australia Symposium held at Swinburne University in Melbourne in February 2014, introduces some of the key questions in the current debates. It also poses the question of whether more satisfactory political and social thought can be produced if scientific reductionism is replaced by a richer and more hermeneutical naturalism, one that takes more account of philosophical anthropology, actual co-involvements of human beings and their environments, and the potential of more naturalistically grounded approaches to culture