Anaplastic Large Cell Lymphoma (ALCL) is a peripheral T cell lymphoma divided into three distinct entities: ALCL, Anaplastic Lymphoma Kinase (ALK)+, ALCL ALK- and cutaneous ALCL. In the majority of ALCL, ALK+, ALK is expressed as the result of a chromosomal translocation generating Nucleophosmin 1(NPM)-ALK, which is considered the main driver. ALCL have an unusual immunophenotype; they rarely express a T cell receptor (TCR), but are often positive for CD4 and produce cytotoxic proteins such as perforin and Granzyme B, but in the absence of CD8, questioning the origin and pathogenesis of this malignancy. Expression of NPM-ALK in mice from the T-cell specific CD4 promoter gives rise to thymic lymphomas not modelling human ALCL suggesting that...
Anaplastic Large T Cell Lymphoma (ALCL) is characterized by high expression of P-Selectin Glycoprote...
Systemic anaplastic large cell lymphoma (ALCL) is a rare, aggressive CD30-positive non-Hodgkin lymph...
In this issue of Blood, Parrilla Castellar et al present a large cohort of anaplastic lymphoma kinas...
Anaplastic large cell lymphoma (ALCL) is a peripheral T-cell lymphoma presenting mostly in children ...
Anaplastic large cell lymphoma (ALCL) is a main type of T-cell lymphomas and comprises three distinc...
T-cell non-Hodgkin lymphoma is a heterogeneous disease ranging from malignancies arising from thymic...
PURPOSE: To unravel the regulatory network underlying nucleophosmin-anaplastic lymphoma kinase (NPM-...
Simple Summary: Anaplastic large cell lymphoma (ALCL) is a lymphoid malignancy considered to be deri...
Purpose. To unravel the regulatory network underlying nucleophosmin-anaplastic lymphoma kinase (NPM-...
Anaplastic large-cell lymphomas (ALCLs) are a group of clinically and biologically heterogeneous dis...
T cell Non-Hodgkin lymphoma is a heterogeneous disease ranging from malignancies arising from thymic...
The discovery by Morris SW et al. in 1994 of the genes contributing to the t(2;5)(p23;q35) transloca...
Anaplastic large-cell lymphomas (ALCLs) are a group of clinically and biologically heterogeneous dis...
The t(2;5)(p23;q35) translocation associated with CD30-positive anaplastic large cell lymphoma resul...
The anaplastic large cell lymphoma kinase (ALK)-positive anaplastic large cell lymphoma (ALCL) is a ...
Anaplastic Large T Cell Lymphoma (ALCL) is characterized by high expression of P-Selectin Glycoprote...
Systemic anaplastic large cell lymphoma (ALCL) is a rare, aggressive CD30-positive non-Hodgkin lymph...
In this issue of Blood, Parrilla Castellar et al present a large cohort of anaplastic lymphoma kinas...
Anaplastic large cell lymphoma (ALCL) is a peripheral T-cell lymphoma presenting mostly in children ...
Anaplastic large cell lymphoma (ALCL) is a main type of T-cell lymphomas and comprises three distinc...
T-cell non-Hodgkin lymphoma is a heterogeneous disease ranging from malignancies arising from thymic...
PURPOSE: To unravel the regulatory network underlying nucleophosmin-anaplastic lymphoma kinase (NPM-...
Simple Summary: Anaplastic large cell lymphoma (ALCL) is a lymphoid malignancy considered to be deri...
Purpose. To unravel the regulatory network underlying nucleophosmin-anaplastic lymphoma kinase (NPM-...
Anaplastic large-cell lymphomas (ALCLs) are a group of clinically and biologically heterogeneous dis...
T cell Non-Hodgkin lymphoma is a heterogeneous disease ranging from malignancies arising from thymic...
The discovery by Morris SW et al. in 1994 of the genes contributing to the t(2;5)(p23;q35) transloca...
Anaplastic large-cell lymphomas (ALCLs) are a group of clinically and biologically heterogeneous dis...
The t(2;5)(p23;q35) translocation associated with CD30-positive anaplastic large cell lymphoma resul...
The anaplastic large cell lymphoma kinase (ALK)-positive anaplastic large cell lymphoma (ALCL) is a ...
Anaplastic Large T Cell Lymphoma (ALCL) is characterized by high expression of P-Selectin Glycoprote...
Systemic anaplastic large cell lymphoma (ALCL) is a rare, aggressive CD30-positive non-Hodgkin lymph...
In this issue of Blood, Parrilla Castellar et al present a large cohort of anaplastic lymphoma kinas...