Positron detection in silica monoliths for miniaturised quality control of PET radiotracers
- Archibald, Stephen J.
- Brown, Nathaniel J.
- Pamme, Nicole
- Maneuski, Dzmitry
- O’Shea, Val
- Pimlott, Sally L.
- Tarn, Mark D.
- Alexander, Richard
Publication date
March 2016
DOI Publisher
Royal Society of Chemistry Language
EnglishAbstract
We demonstrate the use of the miniaturised Medipix positron sensor for detection of the clinical PET radiotracer, [⁶⁸Ga]gallium-citrate, on a silica-based monolith, towards microfluidic quality control. The system achieved a far superior signal-to-noise ratio compared to conventional sodium iodide-based radio-HPLC detection and allowed real-time visualisation of positrons in the monolith
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