Complexity of resistance mechanisms to imipenem in intensive care unit strains of Pseudomonas aeruginosa

International audiencePseudomonas aeruginosa can become resistant to carbapenems by both intrinsic (mutation-driven) and transferable (β-lactamase-based) mechanisms. Knowledge of the prevalence of these various mechanisms is important in intensive care units (ICUs) in order to define optimal prevention and therapeutic strategies