Detection and clinical significance of inflammatory cytokines, procalcitioninand endotoxin in neonatalsepticemia

Objective: To investigate the clinical significance of detection of inflammatory cytokines, procalcitionin and endotoxin in neonatal septicemia. Methods: A total of 84 cases of neonatal septicemia in our hospital from January 2013 to January 2016 were selected as observation group, and 80 cases of neonates without infection signs of the same period were selected as control group. In the early stage of admission before medication and in recovery period, the fasting venous blood was drawn respectively in the observation group, detection of IL-6, IL-8, PCT and endotoxin. In the control group, disposable blood sampling at admission to detect the above indexes. Results: Upon admittance, the levels of IL-6, IL-8, PCT and endotoxin in observation group were significantly higher than those in the control group (P<0.05); in recovery period, the levels of IL-6, IL-8, PCT and endotoxin in observation group were significantly lower than before treatment (P