<p><em>The article presents literature review on the role of B-lymphocytes in pathogenesis of rheumatologic diseases and on the administration of chimeric anti-CD20 monoclonal antibodies — rituximab — for treatment of systemic lupus erythematosus, systemic vasculitis, juvenile dermatomyositis, and juvenile arthritis in children. Results of studies showed that rituximab has good tolerability, efficacy and safety in children’s rheumatologic practice.</em><strong><em></em></strong></p><p><strong><em>Key words: children, B-lymphocytes, rituximab, treatment, depletion.</em></strong><br /><span style="text-decoration: underline;"><em>(<em><em>Voprosy sovremennoi pediatrii — </em></em>Current Pediatrics. – 2010;9(3):<em>54-62</em>)</em></span></p
<em>The management of severe juvenile rheumatoid arthritis (JRA) is a complicated problem. The effic...
<em>The article presents the case report of a child with juvenile rheumatoid arthritis, systemic typ...
<em>This article contains results of the research of tocilizumab treatment efficacy and safety in 39...
<em>The article describes the clinical case of a difficult systemic juvenile arthritis refractory to...
<em>The article describes the run of the severe systemic juvenile rheumatoid arthritis, which is res...
<em>The article contains clinical case description of a severe systemic juvenile rheumatoid arthriti...
<em>The article gives a case report on patient with severe systemic type of juvenile arthritis, refr...
<em>The article presents a case report of severe clinical course of systemic type of juvenile rheuma...
<p><em>The article observes the data on the role of interleukin (IL) 6 in pathogenesis of rheumatoid...
The article presents data on unique worldwide experience of biologic agents use in pediatric rheumat...
<em>Case report about early debut and severe clinical course of system type of juvenile rheumatoid a...
<em>The article presents a case report of severe course of nodular polyarteritis. The disease was hi...
<em>The article presents a case report of severe juvenile rheumatoid arthritis with uveitis, refract...
Objectives: We aim to report the efficacy and safety of rituximab (RTX) in patients diagnosed with j...
<em>The case of early onset and severe course of systemic juvenile rheumatoid arthritis refractory t...
<em>The management of severe juvenile rheumatoid arthritis (JRA) is a complicated problem. The effic...
<em>The article presents the case report of a child with juvenile rheumatoid arthritis, systemic typ...
<em>This article contains results of the research of tocilizumab treatment efficacy and safety in 39...
<em>The article describes the clinical case of a difficult systemic juvenile arthritis refractory to...
<em>The article describes the run of the severe systemic juvenile rheumatoid arthritis, which is res...
<em>The article contains clinical case description of a severe systemic juvenile rheumatoid arthriti...
<em>The article gives a case report on patient with severe systemic type of juvenile arthritis, refr...
<em>The article presents a case report of severe clinical course of systemic type of juvenile rheuma...
<p><em>The article observes the data on the role of interleukin (IL) 6 in pathogenesis of rheumatoid...
The article presents data on unique worldwide experience of biologic agents use in pediatric rheumat...
<em>Case report about early debut and severe clinical course of system type of juvenile rheumatoid a...
<em>The article presents a case report of severe course of nodular polyarteritis. The disease was hi...
<em>The article presents a case report of severe juvenile rheumatoid arthritis with uveitis, refract...
Objectives: We aim to report the efficacy and safety of rituximab (RTX) in patients diagnosed with j...
<em>The case of early onset and severe course of systemic juvenile rheumatoid arthritis refractory t...
<em>The management of severe juvenile rheumatoid arthritis (JRA) is a complicated problem. The effic...
<em>The article presents the case report of a child with juvenile rheumatoid arthritis, systemic typ...
<em>This article contains results of the research of tocilizumab treatment efficacy and safety in 39...