Acute kidney injury in HIV‐infected children: comparison of patients according to the use of highly active antiretroviral therapy
- Douglas de Sousa Soares
- Malena Gadelha Cavalcante
- Samille Maria Vasconcelos Ribeiro
- Rayana Café Leitão
- Ana Patrícia Freitas Vieira
- Roberto da Justa Pires Neto
- Geraldo Bezerra da Silva Junior
- Elizabeth de Francesco Daher
DOIAbstract
Objective: To assess clinical and laboratory data, and acute kidney injury (AKI) in HIV‐infected children using and not using highly active antiretroviral therapy (HAART) prior to admission. Methods: A retrospective study was conducted with HIV‐infected pediatric patients (<16 years). Children who were using and not using HAART prior to admission were compared. Results: Sixty‐three patients were included. Mean age was 5.3 ± 4.27 years; 55.6% were females. AKI was observed in 33 (52.3%) children. Patients on HAART presented lower levels of potassium (3.9 ± 0.8 vs. 4.5 ± 0.7 mEq/L, p = 0.019) and bicarbonate (19.1 ± 4.9 vs. 23.5 ± 2.2 mEq/L, p = 0.013) and had a higher estimated glomerular filtration rate (102.2 ± 36.7 vs. 77.0 ± 32.8 mL/min/...
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