Genetic study on moyamoya disease

Moyamoya disease (MMD) is a chronic progressive obstructive cerebrovascular disease. At present, the etiology and pathogenesis of MMD are still not clear. Recently, many studies confirmed the genetic susceptibility of MMD and reported that the genetic factors are more important than acquired causes. We summarize the domestic and foreign studies on the genetics of MMD, and expect to provide a guidance for early diagnosis and precise treatment. DOI: 10.3969/j.issn.1672-6731.2017.12.01