Seroprevalence of HIV and Hepatitis B Virus Infection and Related Risk Factors Among Injection Drug Users in Kashan

Background: Drug injection is one of the most important risk factor for human immunodeficiency virus (HIV) and viral hepatitis B virus (HBV) infection. The present study was performed to evaluate the seroprevalence of HBV and HIV infection among injecting drug users (IDUs) and to identify the related risk factors for these infections in this group. Methods: This descriptive-analytical study was carried out on three hundred IDUs coming to MMT, DIC and behavior counseling centers in kashan in 2009. questionnaires consisting of demographic information and related risk factors of HBV, HIV infection were filled through interviews. After taking consent , 5 cc blood were obtained. HBV and HIV infection using enzyme-linked immunosorbent assay(ELISA) were examined HIV positive cases were confirmed by western blot. Data analyzed using Spss (version 16). and K square and fisher exat test. Results: 288(96%) out of 300 IDUs, were male and 12(4%)were female. The majority of IDUs 127(42. 3%) were in 30-39 age group with mean age 34. 9±9. 7. (Min:17,Max 68). The majority of IDUs 224(74. 7%) had more than 10 years history of addiction .The age range of onset addiction was 15-20 year in the most of cases 134(44. 7%). The prevalence of HIV was 7(2. 3%), and HBsAg+2(0. 7%). There was no coinfection HIV and HBV. Conclusion: According to High risk behaviors in IDUs and identified HIV cases among them, periodic screening of IDU, HBV vaccination and treatment of addiction and development of MMT centers to prevent of these infections is recommended