Background: Assessing immune response after rotavirus vaccination consists in measuring serum or plasma IgA and IgG antibodies, but these assays provide very little information about the mucosal immune response. Thus the development of assays for detection of mucosal immune response following rotavirus vaccination is essential. We evaluate to assess circulating antibody-secreting cells (ASCs) as a potential means to evaluate mucosal immune responses to rotavirus vaccine. Methods: 372 subjects, aged 6 weeks, were enrolled in the study. All the subjects were assigned to receive two doses of Rotarix® vaccine. Using a micro-modified whole blood-based ELISPOT assay, circulating rotavirus type-specific IgA- and IgG-ASCs, including gut homing β7+ ...
Serum antibodies play an important role in natural protection from rotavirus infection and disease, ...
219-228Annual deaths in infants and young children due to rotavirus (RV) infection are around 100,00...
Background The “gold standard ” for assessing mucosal immunity after vaccination with poliovirus vac...
Abstract Group A rotaviruses (RVA) remain a leading cause of pediatric diarrhea worldwide, in part d...
The reliability of saliva as an indicator of rotavirus infection was assessed among 15 infants (3-12...
Serum rotavirus IgA responses are an imperfect non-mechanistic correlate of protection, and the lack...
Rotaviruses are the most important cause of infectious diarrhea in children throughout the world. Pr...
AbstractAimThis study was undertaken to compare the immunogenicity of a three dose and five dose sch...
Rotavirus is the most important cause of severe gastroenteritis in children under five years of age ...
Published by Oxford University Press for the Infectious Diseases Society of America 2017. This work ...
BACKGROUND:The "gold standard" for assessing mucosal immunity after vaccination with poliovirus vacc...
Background: The "gold standard" for assessing mucosal immunity after vaccination with poliovirus vac...
The lower immune response and efficacy of live oral rotavirus (RV) vaccines tested in developing cou...
Aim: This study was undertaken to assess the immunogenicity, reactogenicity and safety of two doses ...
The “gold standard” for assessing mucosal immunity after vaccination with poliovirus vaccines consis...
Serum antibodies play an important role in natural protection from rotavirus infection and disease, ...
219-228Annual deaths in infants and young children due to rotavirus (RV) infection are around 100,00...
Background The “gold standard ” for assessing mucosal immunity after vaccination with poliovirus vac...
Abstract Group A rotaviruses (RVA) remain a leading cause of pediatric diarrhea worldwide, in part d...
The reliability of saliva as an indicator of rotavirus infection was assessed among 15 infants (3-12...
Serum rotavirus IgA responses are an imperfect non-mechanistic correlate of protection, and the lack...
Rotaviruses are the most important cause of infectious diarrhea in children throughout the world. Pr...
AbstractAimThis study was undertaken to compare the immunogenicity of a three dose and five dose sch...
Rotavirus is the most important cause of severe gastroenteritis in children under five years of age ...
Published by Oxford University Press for the Infectious Diseases Society of America 2017. This work ...
BACKGROUND:The "gold standard" for assessing mucosal immunity after vaccination with poliovirus vacc...
Background: The "gold standard" for assessing mucosal immunity after vaccination with poliovirus vac...
The lower immune response and efficacy of live oral rotavirus (RV) vaccines tested in developing cou...
Aim: This study was undertaken to assess the immunogenicity, reactogenicity and safety of two doses ...
The “gold standard” for assessing mucosal immunity after vaccination with poliovirus vaccines consis...
Serum antibodies play an important role in natural protection from rotavirus infection and disease, ...
219-228Annual deaths in infants and young children due to rotavirus (RV) infection are around 100,00...
Background The “gold standard ” for assessing mucosal immunity after vaccination with poliovirus vac...