<p>Cardiomyocytes were isolated from neonatal rats and grown to confluency. Cells were treated with Ad-CMV-LacZ (control), Ad-CMV-dnMSTAT, or Ad-CMV-MSTAT at MOI = 100 for 18 hours in the presence or absence of PE stress (100 uM). Each condition was tested n = 4 times. (A) Cell number was counted at 40X in 3 fields for each treatment. (B) NCM surface area was quantified in 3 fields at 40X using Fovea Pro software after laminin staining, and representative images are displayed. Approximately 500–800 cells were counted per condition. *p<0.05 vs. LacZ Con (ANOVA).</p
<p>In this study, PE was used to model cardiac stress. This led to early (15 minute) activation of t...
We have previously reported negative inotropic effects of cytokines on papillary muscles that were b...
<p>A. Photomicrographs of representative transverse sections of NLC CHF and Tg-CTGF CHF mice 4 weeks...
<p>NCM's were cultured as described above. Cells were treated with Ad-CMV-LacZ (control), Ad-CMV-dnM...
<p>Cardiomyocytes were isolated from neonatal rats and grown to confluency. Cells were treated with ...
<p>Neonatal C57 mice (day 4–5) were treated with either Saline, AAV9-LacZ, AAV9-dnMSTAT, or AAV9-MST...
<p>Cardiomyocytes were isolated from neonatal rats and grown to confluency. Cells were then stressed...
Myostatin is well established as a negative regulator of skeletal muscle growth, but its role in the...
Myostatin is well established as a negative regulator of skeletal muscle growth, but its role in the...
<p>Cardiomyocytes were isolated from neonatal rats and grown to confluency. Cells were treated with ...
Myostatin is well established as a negative regulator of skeletal muscle growth, and it may play a r...
Objectives: Myostatin, a member of the transforming growth factor-beta (TGF-beta) family, plays a ke...
<p>Neonatal C57 mice (day 4–5) were treated with either Saline (n = 12), AAV9-LacZ (n = 11), AAV9-dn...
<p>Neonatal C57 mice (day 4–5) were treated with either Saline (n = 12), AAV9-LacZ (n = 11), AAV9-dn...
Objectives: Myostatin, a negative regulator of muscle growth, is increased in hypertrophied and infa...
<p>In this study, PE was used to model cardiac stress. This led to early (15 minute) activation of t...
We have previously reported negative inotropic effects of cytokines on papillary muscles that were b...
<p>A. Photomicrographs of representative transverse sections of NLC CHF and Tg-CTGF CHF mice 4 weeks...
<p>NCM's were cultured as described above. Cells were treated with Ad-CMV-LacZ (control), Ad-CMV-dnM...
<p>Cardiomyocytes were isolated from neonatal rats and grown to confluency. Cells were treated with ...
<p>Neonatal C57 mice (day 4–5) were treated with either Saline, AAV9-LacZ, AAV9-dnMSTAT, or AAV9-MST...
<p>Cardiomyocytes were isolated from neonatal rats and grown to confluency. Cells were then stressed...
Myostatin is well established as a negative regulator of skeletal muscle growth, but its role in the...
Myostatin is well established as a negative regulator of skeletal muscle growth, but its role in the...
<p>Cardiomyocytes were isolated from neonatal rats and grown to confluency. Cells were treated with ...
Myostatin is well established as a negative regulator of skeletal muscle growth, and it may play a r...
Objectives: Myostatin, a member of the transforming growth factor-beta (TGF-beta) family, plays a ke...
<p>Neonatal C57 mice (day 4–5) were treated with either Saline (n = 12), AAV9-LacZ (n = 11), AAV9-dn...
<p>Neonatal C57 mice (day 4–5) were treated with either Saline (n = 12), AAV9-LacZ (n = 11), AAV9-dn...
Objectives: Myostatin, a negative regulator of muscle growth, is increased in hypertrophied and infa...
<p>In this study, PE was used to model cardiac stress. This led to early (15 minute) activation of t...
We have previously reported negative inotropic effects of cytokines on papillary muscles that were b...
<p>A. Photomicrographs of representative transverse sections of NLC CHF and Tg-CTGF CHF mice 4 weeks...