Procaine-induced inhibition of SEG neural activity depresses cockroach locomotion.

<p>A. Extracellular bipolar recording of spiking activity in the SEG of a non-stung cockroach. Transient (1 min, red bar) application of the sodium-channel blocker, procaine, completely and reversibly abolishes neuronal activity in the ganglion. B. Behavioral analysis of non-stung cockroaches injected with saline (black bars) or procaine into the SEG (red bars) or the SupEG (green bars). Spontaneous walking (top) and evoked escape responses (bottom) are reversibly suppressed by the inhibition of neuronal activity in the SEG but not of the SupEG. ***p<0.001, as compared with controls.