<p><b>A.</b> CYP51<sub>Tc</sub> (cyan in <b>A</b>, <b>B</b> and <b>C</b>, PDB ID Code 2WUZ) and CYP51<sub>Tb</sub> (wheat, PDB ID Code 2WV2) superimposed with r.m.s.d. of 0.89 Å. Helices are represented by labeled cylinders. Fluconazole is omitted for clarity. <b>B.</b> CYP51<sub>Tc</sub> and CYP51<sub>Mt</sub> (golden yellow, PDB ID Code 2VKU) superimposed with r.m.s.d of 1.83 Å. <b>C.</b> CYP51<sub>Tc</sub> and CYP51<sub>h</sub> (lemon green, PDB ID Code: 3I3K) superimposed with r.m.s.d of 1.45 Å. In each panel, distal surface is shown on the right. Image on the left is rotated ∼90° toward viewer.</p
<p>Comparison of the deduced amino acid sequence of CYP2D49 with the sequences of other CYP2D isofor...
Sterol 14α-demethylase (P45014DM) encoded by CYP51 is a member of the cytochrome P450 (CYP) gene sup...
<p>3D-models for CYP53C2 from <i>Phanerochaete chrysosporium</i> (Pchr) <a href="http://www.plosone....
<p>Values ± standard error are shown. <sup>a</sup> p-values are for comparison between HKO+C and HKO...
<p><b>A, B.</b> Fluconazole-bound CYP51<sub>Tc</sub> with selected α-helices labeled (PDB ID Code 2W...
<p>Values ± standard error are shown. <sup>a</sup> p-values are for comparison between HKO+C and HKO...
<p>Main panel shows the absolute protein spectrum, while insert shows CO-bound reduced difference sp...
Cytochrome P450 51 (CYP51) is sterol 14a-demethylase, known also as Erg11p in yeast. First studied i...
Sterol 14α-demethylase (CYP51), a major checkpoint in membrane sterol biosynthesis, is a key target ...
<p>Structural comparison of Δ<sup>9</sup>-THC (1), the synthetic CP55,940 (4), tetrahydromagnolol (1...
<p>Soret and visible regions of the CYP51<sub>Tc</sub> (<b>A</b>) and CYP51<sub>Tb</sub> (<b>B</b>) ...
<p>A) X-ray structure of CYP51 (green cartoon representation with heme cofactor as sticks with bound...
CYP51 encodes the target site of the azole class of fungicides widely used in plant protection. Some...
<p><i>A,</i> Structural superposition, through the receiver domain, of a full-length ChxR monomer (c...
<p>Multiple alignment of CYP450 proteins from <i>S</i>. <i>mansoni</i> (csm305A); rabbit CYP450 2C5 ...
<p>Comparison of the deduced amino acid sequence of CYP2D49 with the sequences of other CYP2D isofor...
Sterol 14α-demethylase (P45014DM) encoded by CYP51 is a member of the cytochrome P450 (CYP) gene sup...
<p>3D-models for CYP53C2 from <i>Phanerochaete chrysosporium</i> (Pchr) <a href="http://www.plosone....
<p>Values ± standard error are shown. <sup>a</sup> p-values are for comparison between HKO+C and HKO...
<p><b>A, B.</b> Fluconazole-bound CYP51<sub>Tc</sub> with selected α-helices labeled (PDB ID Code 2W...
<p>Values ± standard error are shown. <sup>a</sup> p-values are for comparison between HKO+C and HKO...
<p>Main panel shows the absolute protein spectrum, while insert shows CO-bound reduced difference sp...
Cytochrome P450 51 (CYP51) is sterol 14a-demethylase, known also as Erg11p in yeast. First studied i...
Sterol 14α-demethylase (CYP51), a major checkpoint in membrane sterol biosynthesis, is a key target ...
<p>Structural comparison of Δ<sup>9</sup>-THC (1), the synthetic CP55,940 (4), tetrahydromagnolol (1...
<p>Soret and visible regions of the CYP51<sub>Tc</sub> (<b>A</b>) and CYP51<sub>Tb</sub> (<b>B</b>) ...
<p>A) X-ray structure of CYP51 (green cartoon representation with heme cofactor as sticks with bound...
CYP51 encodes the target site of the azole class of fungicides widely used in plant protection. Some...
<p><i>A,</i> Structural superposition, through the receiver domain, of a full-length ChxR monomer (c...
<p>Multiple alignment of CYP450 proteins from <i>S</i>. <i>mansoni</i> (csm305A); rabbit CYP450 2C5 ...
<p>Comparison of the deduced amino acid sequence of CYP2D49 with the sequences of other CYP2D isofor...
Sterol 14α-demethylase (P45014DM) encoded by CYP51 is a member of the cytochrome P450 (CYP) gene sup...
<p>3D-models for CYP53C2 from <i>Phanerochaete chrysosporium</i> (Pchr) <a href="http://www.plosone....