Anxiety-related behaviors during social interaction in GSK3 knockin mice.

<p>A. During the sociability period, there was not a significant difference in grooming times of GSK3 knockin (KI) mice and wild-type (WT) mice, but the percentage of wild-type (WT) mice with grooming times above the median was higher than GSK3 knockin (KI) mice. Dashed lines represent median grooming times, 12.5 sec. B. GSK3 KI mice spent significantly less time rearing and digging than WT mice during the sociability period. * p<0.05 compared to untreated WT mice. C. During the social preference period, there was not a significant difference in grooming times of GSK3 knockin (KI) mice and wild-type (WT) mice, but the percentage of KI mice with grooming times above the median was slightly higher than WT controls. Dashed lines represent median grooming times, 12.5 sec. D. WT and GSK3 KI mice spent similar times rearing and digging during the social preference period.