Predicted HLA-E binding Mtb peptides induce T-cell proliferation.

<p>CFSE-labeled PBMCs of 20 donors were stimulated with 10 µg/ml of peptide in the presence of IL-7, on day 7 low dose IL-2 was added and at day 10 proliferation was assessed by flowcytometry. Plots are gated on CD3⁺CD8⁺CD56⁻ cells in the lymphocyte gate, the percentage of proliferation indicated is within CD3⁺CD8⁺CD56⁻ cells. Peptide and donor numbers correspond to the numbers in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1000782#ppat-1000782-t001" target="_blank">Table 1</a>.