Cyr61 prevents U937 cell adhesion to vitronectin.

<p>uPAR-bearing U937 cells were incubated for 120 minutes with VTNC-coated wells previously incubated with buffer or Cyr61 or PAI-1 (1.5 µM) as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0009356#s4" target="_blank">Materials and Methods</a>. As a control, wells were coated with gelatin only. One hundred % cell adhesion was estimated in the presence of buffer (vehicle) only, and 0% as adhesion to gelatin. Results from quintuplicate experiments are shown.