<p>Panel A, values of HPRT sequences; Panel B values of G6PD sequences. AH, AT, BH, BT: values calculated for cDNA clones of Tumour and nearby Healthy tissues of patients A and B. C1 and C2: values for cDNA clones from blood tissues of 2 healthy reference individuals. AT gene: values for clones of global genomic regions of DNA from tumour tissues of patient A. AT exons: values for the exon regions of the sequenced genomic regions. Controls: values for clone samples.</p
<p>Panel A shows box plots with the distribution of tumors (n = 31) according to the percentage of t...
<p>* Changes are defined as being within coding regions or at intron-exon boundaries and have a Phre...
<p>Numeration of nucleotide positions of exons starts from A of the initial ATG triplet of the codin...
<p>Panel A, values of HPRT transcripts; Panel B, values of G6PD transcripts. Panel C, values of HPRT...
<p>(A) Pie charts of hypermutation per IgV<sub>H</sub> region for indicated Ramos B cell transductan...
A) Number of clones in human tumors within each tumor type. Tumor types are ranked by median number ...
<p>The group median for CDR1/2 in each of the 5 most frequently expressed V<sub>H</sub>3 genes (V<su...
<p>“% C nucleotides mutated” indicates the proportion of nucleotides in either the CDR1/2 or FR1/2/3...
<p>(A) Clustering of whole exome sequencing mutation data based on the mutation status of the genes ...
We have analyzed the sequence heterogeneity of the transcripts of the human HPRT and G6PD single cop...
<p><b>A</b>–<b>B</b>. Comparison of the variant allelic frequency of mutations detected using whole ...
<p>(A, B) Number and distribution of mutations per clone after error-prone PCR mediated mutagenesis ...
<p>To compute the degradation frequencies, the number of changes between the consensus sequence and ...
<p>Mutation frequency was calculated over the V-gene and J-gene as nucleotides or amino acids differ...
<p>A: Representative amplification plots of plasmid containing <i>JAK2</i> exon 12 mutation diluted ...
<p>Panel A shows box plots with the distribution of tumors (n = 31) according to the percentage of t...
<p>* Changes are defined as being within coding regions or at intron-exon boundaries and have a Phre...
<p>Numeration of nucleotide positions of exons starts from A of the initial ATG triplet of the codin...
<p>Panel A, values of HPRT transcripts; Panel B, values of G6PD transcripts. Panel C, values of HPRT...
<p>(A) Pie charts of hypermutation per IgV<sub>H</sub> region for indicated Ramos B cell transductan...
A) Number of clones in human tumors within each tumor type. Tumor types are ranked by median number ...
<p>The group median for CDR1/2 in each of the 5 most frequently expressed V<sub>H</sub>3 genes (V<su...
<p>“% C nucleotides mutated” indicates the proportion of nucleotides in either the CDR1/2 or FR1/2/3...
<p>(A) Clustering of whole exome sequencing mutation data based on the mutation status of the genes ...
We have analyzed the sequence heterogeneity of the transcripts of the human HPRT and G6PD single cop...
<p><b>A</b>–<b>B</b>. Comparison of the variant allelic frequency of mutations detected using whole ...
<p>(A, B) Number and distribution of mutations per clone after error-prone PCR mediated mutagenesis ...
<p>To compute the degradation frequencies, the number of changes between the consensus sequence and ...
<p>Mutation frequency was calculated over the V-gene and J-gene as nucleotides or amino acids differ...
<p>A: Representative amplification plots of plasmid containing <i>JAK2</i> exon 12 mutation diluted ...
<p>Panel A shows box plots with the distribution of tumors (n = 31) according to the percentage of t...
<p>* Changes are defined as being within coding regions or at intron-exon boundaries and have a Phre...
<p>Numeration of nucleotide positions of exons starts from A of the initial ATG triplet of the codin...