<p>Mice were intramuscularly immunized with 0.1 µg of VLPs once or twice, and were challenged with a lethal dose of A/California/04/2009 (10 LD<sub>50</sub>) (n = 6) day 10 post immunization. Mice were observed daily to monitor changes in body weight and to record mortality (25% loss in body weight as the IACUC endpoint).</p
<p>At week 5, mice vaccinated with clade 2-dervied vaccines were challenged intranasally with a leth...
<p>BALB/c mice (n = 6) were immunized on day 0 and 21 with rNP (10 µg/dose) alone or co-administered...
<p>Mice (groups of 5) were mock-immunized with PBS or immunized with either 10<sup>3</sup> or 10<sup...
<p>A–B: Protection against A/California/04/2009 virus challenge. Mice intramuscularly immunized with...
<p>Mice were vaccinated once with mammalian cell-, or baculovirus- derived VLPs containing 50 ng of ...
<div><p>(A) Three groups of mice were vaccinated with escalating doses of VV-hTAP1,2 (3e3 PFU, 3e4 P...
<p>At week 30 post immunization, H5N1 VLP immunized and control (PBS or 5 µg inactivated PR/8/34 H1N...
<p>(A–B) At six months after prime-boost immunizations with M2 VLPs, mice (n = 5) were challenged wi...
<p>Mice groups (n = 6–10) immunized with various VLP vaccines and infected with a lethal dose (10× M...
<p>Groups of ten BALB/c mice (3-week-old) were vaccinated with 5×10<sup>4</sup> PFU MVTT1, MVTT2 or ...
<p>PBS or the indicated mAb (100 μg) were transferred by the intraperitoneal route to mice (groups o...
<p>Six-day-old mice were inoculated SC with 5×10<sup>4</sup> PFU of VEEV TC-83 or IRES-based viruses...
<p>A. Body weight loss in vaccinated/challenged C57/B6 mice. Mice were vaccinated with Pol1, Pol2, A...
<p>Five week old AG129 mice received i.m. injections of an adjuvanted inactivated EV71 vaccine. Cont...
<p>At day 42, vaccinated mice were challenged intranasally with a lethal dose (100 LD<sub>50</sub>) ...
<p>At week 5, mice vaccinated with clade 2-dervied vaccines were challenged intranasally with a leth...
<p>BALB/c mice (n = 6) were immunized on day 0 and 21 with rNP (10 µg/dose) alone or co-administered...
<p>Mice (groups of 5) were mock-immunized with PBS or immunized with either 10<sup>3</sup> or 10<sup...
<p>A–B: Protection against A/California/04/2009 virus challenge. Mice intramuscularly immunized with...
<p>Mice were vaccinated once with mammalian cell-, or baculovirus- derived VLPs containing 50 ng of ...
<div><p>(A) Three groups of mice were vaccinated with escalating doses of VV-hTAP1,2 (3e3 PFU, 3e4 P...
<p>At week 30 post immunization, H5N1 VLP immunized and control (PBS or 5 µg inactivated PR/8/34 H1N...
<p>(A–B) At six months after prime-boost immunizations with M2 VLPs, mice (n = 5) were challenged wi...
<p>Mice groups (n = 6–10) immunized with various VLP vaccines and infected with a lethal dose (10× M...
<p>Groups of ten BALB/c mice (3-week-old) were vaccinated with 5×10<sup>4</sup> PFU MVTT1, MVTT2 or ...
<p>PBS or the indicated mAb (100 μg) were transferred by the intraperitoneal route to mice (groups o...
<p>Six-day-old mice were inoculated SC with 5×10<sup>4</sup> PFU of VEEV TC-83 or IRES-based viruses...
<p>A. Body weight loss in vaccinated/challenged C57/B6 mice. Mice were vaccinated with Pol1, Pol2, A...
<p>Five week old AG129 mice received i.m. injections of an adjuvanted inactivated EV71 vaccine. Cont...
<p>At day 42, vaccinated mice were challenged intranasally with a lethal dose (100 LD<sub>50</sub>) ...
<p>At week 5, mice vaccinated with clade 2-dervied vaccines were challenged intranasally with a leth...
<p>BALB/c mice (n = 6) were immunized on day 0 and 21 with rNP (10 µg/dose) alone or co-administered...
<p>Mice (groups of 5) were mock-immunized with PBS or immunized with either 10<sup>3</sup> or 10<sup...