<p>BALB/c mice were infected, the heart harvested on day 14 p.i., the leukocytes isolated and incubated with monensin for 6 h in culture medium, and the intracellular expression of IL-17 (<b>A</b>) and IFN-γ (<b>B</b>) were determined. Data (mean ± SEM) are representative of two independent experiments using five mice per group. * <i>P</i><0.05 compared to infected mice treated with normal rat IgG.</p
<p>A) Cell numbers in spleen, lymph nodes and liver of WT and IL-17RA KO mice determined at differen...
Tbx21 (i.e., T-bet) is an IFN--inducible transcription factor that promotes Th1 differentiation. Pre...
<p>(<b>A</b>) CD4<sup>−</sup>CD8<sup>−</sup> T cells purified by cell sorting using flow cytometry f...
<p>IFN-γ, TNF-α, IL-10, IL-12, and IL-17 were quantified in the sera and heart tissue of infected mi...
<p>A) IL-17A and IL-17F concentration determined in the culture supernatants of spleen and lymph nod...
<p>Splenocytes from BALB/c mice infected (14 days p.i.) or not with <i>T. cruzi</i> were harvested, ...
<p>Leukocytes from BALB/c mice (5×10<sup>6</sup> cells/ml) were cultured with or without trypomastig...
<p>Parasitemia (<b>A</b>), cardiac parasitism (<b>B</b>), and survival (<b>C</b>) were determined in...
<p>The <i>ex vivo</i> frequencies of IL-17<sup>+</sup> cells were determined in total splenocytes (<...
<p>A/J mice were infected with <i>T. cruzi</i> (INF), or immunized with HKTC (HKTC), or PBS (PBS). A...
<p>A/J mice were infected with <i>T. cruzi</i>, or immunized with HKTC, HKLA, or PBS. At 21 d.p.i., ...
. and NK cells from BALB/c mice on the early acute phase of infection. Treatment of infected mice wi...
<p>A) Survival of WT and IL-17RA KO mice after <i>T. cruzi</i> infection, P value calculated with a ...
<p>A) CD11b+Gr-1+ frequency and absolute numbers in blood, spleen and liver of 20-day <i>T. cruzi</i...
Background: Chagas disease is a neglected disease caused by the intracellular parasite Trypanosoma c...
<p>A) Cell numbers in spleen, lymph nodes and liver of WT and IL-17RA KO mice determined at differen...
Tbx21 (i.e., T-bet) is an IFN--inducible transcription factor that promotes Th1 differentiation. Pre...
<p>(<b>A</b>) CD4<sup>−</sup>CD8<sup>−</sup> T cells purified by cell sorting using flow cytometry f...
<p>IFN-γ, TNF-α, IL-10, IL-12, and IL-17 were quantified in the sera and heart tissue of infected mi...
<p>A) IL-17A and IL-17F concentration determined in the culture supernatants of spleen and lymph nod...
<p>Splenocytes from BALB/c mice infected (14 days p.i.) or not with <i>T. cruzi</i> were harvested, ...
<p>Leukocytes from BALB/c mice (5×10<sup>6</sup> cells/ml) were cultured with or without trypomastig...
<p>Parasitemia (<b>A</b>), cardiac parasitism (<b>B</b>), and survival (<b>C</b>) were determined in...
<p>The <i>ex vivo</i> frequencies of IL-17<sup>+</sup> cells were determined in total splenocytes (<...
<p>A/J mice were infected with <i>T. cruzi</i> (INF), or immunized with HKTC (HKTC), or PBS (PBS). A...
<p>A/J mice were infected with <i>T. cruzi</i>, or immunized with HKTC, HKLA, or PBS. At 21 d.p.i., ...
. and NK cells from BALB/c mice on the early acute phase of infection. Treatment of infected mice wi...
<p>A) Survival of WT and IL-17RA KO mice after <i>T. cruzi</i> infection, P value calculated with a ...
<p>A) CD11b+Gr-1+ frequency and absolute numbers in blood, spleen and liver of 20-day <i>T. cruzi</i...
Background: Chagas disease is a neglected disease caused by the intracellular parasite Trypanosoma c...
<p>A) Cell numbers in spleen, lymph nodes and liver of WT and IL-17RA KO mice determined at differen...
Tbx21 (i.e., T-bet) is an IFN--inducible transcription factor that promotes Th1 differentiation. Pre...
<p>(<b>A</b>) CD4<sup>−</sup>CD8<sup>−</sup> T cells purified by cell sorting using flow cytometry f...