Immunohistochemical detection of thymosin β4 in foetal and adult pancreas.

<p><b>a</b>) Foetal pancreas: immunoreactivity for Tβ₄ is localized inside the islets of Langherans. Some of endocrine cells show the entire cytoplasm strongly immunoreactive for the peptide (arrows). Few Tβ₄-reactive cells are also present in the exocrine pancreas, inside the tubular structures (arrowhead). (Original Magnification ×400). <b>b</b>) Adult pancreas: the highest reactivity for Tβ₄ is observed in Langherans islet cells, which show diffuse fine granular deposits in their cytoplasm (arrows). (Original Magnification ×400).