Relationship between drug resistance, predicted RC and treatment experience.

<p>Based on 5475 genotypes from the EuResist database, the distribution of resistance scores and predicted viral RC for different numbers of previous therapies (completed before the date of genotyping) is shown. In the middle box plot, RC was predicted from a model trained on Monogram data; below, RC predictions are based on Erlangen data. The overall Spearman correlation between the number of previous therapies and the resistance score is 0.560; for the number of therapies and predicted RC, we obtain correlation coefficients of −0.336 (Monogram predictions) and −0.231 (Erlangen predictions).