<p>TGR-1, HOmyc3, and HO15.19 cells were left untreated or exposed to IR (20Gy), and further incubated in complete medium for 2h. The levels of phospho-ATM and phospho-H2AX (γH2AX) were assessed by western blot analysis. Actin and total ATM were used as internal loading controls. One of three experiments is shown.</p
textPrecancerous lesions from a variety of human tissues display markers of DNA damage suggesting th...
<p>(A) ATM inhibitor reduces signaling events. Western blot analysis comparing DDR proteins at 18 h....
ATM and ATR are two related kinases essential for signalling DNA damage. Although ATM is thought to ...
<p><b>A</b>) HCT116 cells were transfected either with the control GFP-specific (CTR) or MYC specifi...
AIM: Exposure to ionizing radiation (IR) causes DNA strand break formation, result-ing in the rapid ...
2 ATM-dependent cellular response to DNA double strand breaks plays a pivotal role in the maintenanc...
<p><b>A</b>) TGR-1 and the <i>myc</i> reconstituted HOmyc3 cells were left untreated or exposed to I...
<p>In response to IR or CDT, MYC contributes to activation of the ATM-dependent responses, leading t...
ATM-dependent cellular response to DNA double strand breaks plays a pivotal role in the maintenance ...
H2AX phosphorylation is an early step in the response to DNA damage. It is widely accepted that ATM ...
<p>(<b>A</b>) γH2AX, pS1981-ATM and actin protein expression detected by Western blotting in WT ant ...
H2AX phosphorylation is an early step in the response to DNA damage. It is widely accepted that ATM ...
<p>A, CNE1-LMP1 cells were transfected with ATM-siRNA or Control-siRNA and total cellular protein wa...
The ATM kinase has previously been shown to respond to the DNA damage induced by reoxygenation follo...
The ATM kinase has previously been shown to respond to the DNA damage induced by reoxygenation follo...
textPrecancerous lesions from a variety of human tissues display markers of DNA damage suggesting th...
<p>(A) ATM inhibitor reduces signaling events. Western blot analysis comparing DDR proteins at 18 h....
ATM and ATR are two related kinases essential for signalling DNA damage. Although ATM is thought to ...
<p><b>A</b>) HCT116 cells were transfected either with the control GFP-specific (CTR) or MYC specifi...
AIM: Exposure to ionizing radiation (IR) causes DNA strand break formation, result-ing in the rapid ...
2 ATM-dependent cellular response to DNA double strand breaks plays a pivotal role in the maintenanc...
<p><b>A</b>) TGR-1 and the <i>myc</i> reconstituted HOmyc3 cells were left untreated or exposed to I...
<p>In response to IR or CDT, MYC contributes to activation of the ATM-dependent responses, leading t...
ATM-dependent cellular response to DNA double strand breaks plays a pivotal role in the maintenance ...
H2AX phosphorylation is an early step in the response to DNA damage. It is widely accepted that ATM ...
<p>(<b>A</b>) γH2AX, pS1981-ATM and actin protein expression detected by Western blotting in WT ant ...
H2AX phosphorylation is an early step in the response to DNA damage. It is widely accepted that ATM ...
<p>A, CNE1-LMP1 cells were transfected with ATM-siRNA or Control-siRNA and total cellular protein wa...
The ATM kinase has previously been shown to respond to the DNA damage induced by reoxygenation follo...
The ATM kinase has previously been shown to respond to the DNA damage induced by reoxygenation follo...
textPrecancerous lesions from a variety of human tissues display markers of DNA damage suggesting th...
<p>(A) ATM inhibitor reduces signaling events. Western blot analysis comparing DDR proteins at 18 h....
ATM and ATR are two related kinases essential for signalling DNA damage. Although ATM is thought to ...