ApoE modulates the expression of PPARγ.

<p><b>A</b>: Expression of IL-4Rα1 and of IL-13Rα1 in non-polarized MØ^B6 and MØ^ApoE determined by real time PCR and normalized by HPRT (au: arbitrary unit). <b>B</b>: Expression of PPARγ in non-polarized MØ from MØ^B6 (black) and MØ^ApoE (white) mice with increasing doses of recombinant ApoE (rApoE) determined by real time PCR and normalized by HPRT (au: arbitrary unit). **: p<0.001; ***: p<0.0001 vs MØ^B6. <b>C</b>: Expression of ArgI in M1 and M2 MØ^B6 (black) and MØ^ApoE (white) mice polarized with or without (−) pioglitazone (Pio) or GW9662 (GW) determined by real time PCR. The Results are expressed as 2^−ΔΔCt<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0008852#pone.0008852-Pfaffl1" target="_blank">[30]</a>. *: p<0.05; **: p<0.001 vs matched MØ^B6 condition; †: p<0.05; ††: p<0.01 vs matched M1 condition.