METH self-administration causes reductions in DAT and TH protein levels in the striatum.

<p>(A) Representative immunoblots show expression of TH, DAT and 5-HTT protein levels in the striatum 14 days after last METH self-administration session. (B) Quantitative analyses of immunoblots reveal significant decreases in TH and DAT, but no change in 5-HTT expression in the METH-treated rats. Data presented as mean ± SEM. ** <i>p</i><0.01 vs control. Data were analyzed by ANOVA followed by PLSD, n = 7−11 per group.