Summary of Trx redox status following TR1 knockdown and JS-K treatment: Percent Trx in each redox state (% total).

<p>Summary of the 6 possible redox states of Trx in RKO cells with endogenous TR1 (si-Scramble) or with endogenous TR1 knocked-down (si-TR1) following treatment with 5 µM JS-K for 90 min. Trx does show a shift to more oxidized states in the cells treated with JS-K with TR1 knocked down.