<p>Anti-HA antibody was diluted 100-fold. Immunohistochemical observations were repeated thrice and each observation gave the same result. Ten homozygous transgenic 3-month-old mice were fed B6-deficient food for 3 weeks. Transgenic experimental mice were injected with anti-HA antibody every 3 days. For details, see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0008593#s2" target="_blank">Materials and Methods</a>. CTL, transgenic control mice; Ex, transgenic experimental mice.</p
<p>(A) (B) ME7-inoculated transgenic mouse with clinical signs at 98 dpi showing cerebral cortex wit...
<p>Control mice: 3xTg-AD mice at 3 months and 3 weeks with normal feeding. Control mice showed good ...
<p>Hippocampal brain sections from wild-type (WT) and APΔE9/RanBP9 triple transgenic mice were stain...
<p>Seven-month-old male 3xTg-AD homozygous mice mice fed B6-deficient food for 3 weeks served as the...
<p><b>(A)</b> Fluorescent immunohistostaining of mouse brain slices from transgenic N171-82Q HD mice...
<p>Non-transgenic mice had an average score of 3 mice each day. Hemizygous transgenic control (hemiz...
There have been several reports on the use of b-amyloid (Ab) vaccination in different mouse models o...
<p>(A) Immunostaining of the cerebral cortex of 4-, 8-, and 48-week old mice using NeuN antibody. 4-...
<p>Sections from old wt, young and old (Thy1)-h[A30P]αSYN transgenic mice were stained for human tra...
The gap represents the missing polyQ and polyP domains in this antigen. The black box indicates two ...
Heterologous expression of the functional amyloid beta (A beta) antibody beta 1 in the central nervo...
<p>Note: A: Vaccine treatment was started at 12 months. Three months later, urine was collected an e...
Alzheimer's disease (AD) is histopathologically characterized by neurodegeneration, the formation of...
<p>RNAs were extracted from the brain, spinal cord, and muscle of 5746-infected 7-day old hSCARB2-tr...
<p><i>(A)</i> Equal amounts of brain samples from 7–8 months age of the control APP mice and APP-HFD...
<p>(A) (B) ME7-inoculated transgenic mouse with clinical signs at 98 dpi showing cerebral cortex wit...
<p>Control mice: 3xTg-AD mice at 3 months and 3 weeks with normal feeding. Control mice showed good ...
<p>Hippocampal brain sections from wild-type (WT) and APΔE9/RanBP9 triple transgenic mice were stain...
<p>Seven-month-old male 3xTg-AD homozygous mice mice fed B6-deficient food for 3 weeks served as the...
<p><b>(A)</b> Fluorescent immunohistostaining of mouse brain slices from transgenic N171-82Q HD mice...
<p>Non-transgenic mice had an average score of 3 mice each day. Hemizygous transgenic control (hemiz...
There have been several reports on the use of b-amyloid (Ab) vaccination in different mouse models o...
<p>(A) Immunostaining of the cerebral cortex of 4-, 8-, and 48-week old mice using NeuN antibody. 4-...
<p>Sections from old wt, young and old (Thy1)-h[A30P]αSYN transgenic mice were stained for human tra...
The gap represents the missing polyQ and polyP domains in this antigen. The black box indicates two ...
Heterologous expression of the functional amyloid beta (A beta) antibody beta 1 in the central nervo...
<p>Note: A: Vaccine treatment was started at 12 months. Three months later, urine was collected an e...
Alzheimer's disease (AD) is histopathologically characterized by neurodegeneration, the formation of...
<p>RNAs were extracted from the brain, spinal cord, and muscle of 5746-infected 7-day old hSCARB2-tr...
<p><i>(A)</i> Equal amounts of brain samples from 7–8 months age of the control APP mice and APP-HFD...
<p>(A) (B) ME7-inoculated transgenic mouse with clinical signs at 98 dpi showing cerebral cortex wit...
<p>Control mice: 3xTg-AD mice at 3 months and 3 weeks with normal feeding. Control mice showed good ...
<p>Hippocampal brain sections from wild-type (WT) and APΔE9/RanBP9 triple transgenic mice were stain...