<p>ATA inhibits enzymatic activity of NA (A) derived from PR8, NC, NY and B viruses, (B) recombinant N1 and N4 proteins. Viruses or recombinant proteins were incubated with increasing concentrations of ATA and NA enzymatic activity was determined by a chemiluminescent assay. Samples were tested in quadruplicates and presented as means and standard deviations (error bars).</p
<p>rPR8 M1 N87S and rPR8 M1 R101G viruses have a higher neuraminidase activity than rPR8 wt virus in...
<p>Viruses were pre-incubated with zanamivir (a) or oseltamivir (b) and NA activity was determined. ...
a<p>results of pyrosequencing quantification on isolates obtained after 2 passages on MDCK cells.</p...
<p>Mean concentrations of drugs ± standard deviations that inhibited 50% (IC<sub>50</sub>) of the vi...
<p>(A) NA activity in A/CA and A/tk/TK N1-PPs, and Mock samples was titrated incubating fetuin-coate...
<p>MDCK cells were inoculated with influenza A viruses (MOI 0.001), then treated with ATA for 48 h. ...
<p>(A) Cytotoxicity of ATA in MDCK cells. MDCK cells were treated with ATA for 48 h at the indicated...
<p>Viruses in culture supernatants were detected by ELISA 48 h following treatment with ATA, AH or b...
<p>Influenza PR8, NC, NY and B viruses were pre-incubated with ATA (0, 50, 100 µg/ml) for 30 min, th...
[[abstract]]There is a continuing threat that the highly pathogenic avian influenza virus will cause...
[[abstract]]There is a continuing threat that the highly pathogenic avian influenza virus will cause...
<p>Three-dimensional view of HA trimer (a) and NA tetramer (b). Mutations found in individual viruse...
<p>MDCK cells were infected with influenza A PR8 virus and treated with the indicated concentrations...
Shown is the NA activity of Egyptian H5N1 viruses carrying different mutations against MUNANA (A-G) ...
Aurintricarboxylic acid (ATA) has been shown to inhibit the replication of viruses from several diff...
<p>rPR8 M1 N87S and rPR8 M1 R101G viruses have a higher neuraminidase activity than rPR8 wt virus in...
<p>Viruses were pre-incubated with zanamivir (a) or oseltamivir (b) and NA activity was determined. ...
a<p>results of pyrosequencing quantification on isolates obtained after 2 passages on MDCK cells.</p...
<p>Mean concentrations of drugs ± standard deviations that inhibited 50% (IC<sub>50</sub>) of the vi...
<p>(A) NA activity in A/CA and A/tk/TK N1-PPs, and Mock samples was titrated incubating fetuin-coate...
<p>MDCK cells were inoculated with influenza A viruses (MOI 0.001), then treated with ATA for 48 h. ...
<p>(A) Cytotoxicity of ATA in MDCK cells. MDCK cells were treated with ATA for 48 h at the indicated...
<p>Viruses in culture supernatants were detected by ELISA 48 h following treatment with ATA, AH or b...
<p>Influenza PR8, NC, NY and B viruses were pre-incubated with ATA (0, 50, 100 µg/ml) for 30 min, th...
[[abstract]]There is a continuing threat that the highly pathogenic avian influenza virus will cause...
[[abstract]]There is a continuing threat that the highly pathogenic avian influenza virus will cause...
<p>Three-dimensional view of HA trimer (a) and NA tetramer (b). Mutations found in individual viruse...
<p>MDCK cells were infected with influenza A PR8 virus and treated with the indicated concentrations...
Shown is the NA activity of Egyptian H5N1 viruses carrying different mutations against MUNANA (A-G) ...
Aurintricarboxylic acid (ATA) has been shown to inhibit the replication of viruses from several diff...
<p>rPR8 M1 N87S and rPR8 M1 R101G viruses have a higher neuraminidase activity than rPR8 wt virus in...
<p>Viruses were pre-incubated with zanamivir (a) or oseltamivir (b) and NA activity was determined. ...
a<p>results of pyrosequencing quantification on isolates obtained after 2 passages on MDCK cells.</p...