FLPo expression and activity in different tissues.

<p>(A) PCR genotyping of Neo cassette removal in different tissues of F1 offsprings. (B) PCR of different tissues [testis(T), ovary(O) liver(L) brain(B)muscle(M) kidney(K) heart(H)] of 4 WL mice with (WLFo) or without (WL) the FLPo transgene. Using primer sets as specified in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0008054#pone-0008054-g002" target="_blank">Fig. 2</a>. we found recombination in all tissues when the FLPo transgene was present. * indicates PCR positive control using S6/LoxP-A primer set for amplification of Neo cassette.