<p>A, simulation of proximal (soma) and distal EPSCs seen with electrode placed at the soma. Distal synapse is at dendrite 0.95; assuming 0 as the proximal end and 1 as the distal end. Both synapses have the same kinetics and g<sub>M</sub> (9.2*10<sup>−5</sup> µS). The EPSC decay was fitted with an exponential. B, the electrotonic delay of the EPSC propagation to the soma as a function of the synapse location at the dendrite. The delay was measured to the moment when the EPSC seen at the soma reached 10% of its amplitude. C, the EPSC rise time (from 10% to 80%) as a function of the synapse location. D, simulation of proximal (soma) and distal (dendrite 0.95) EPSPs seen at the soma. The decay of the distal EPSP is fitted with one exponential...
<p>A: Histogram showing EPSP amplitude distribution for N = 100 simulated neurons with 130 primary a...
1. Computer simulations were used to study the effect of voltage-dependent calcium and potassium con...
1. Computer simulations were used to study the effect of voltage-dependent calcium and potassium con...
<p>Electrotonic attenuation of the synaptic current along the dendrites en route to the soma, result...
<p>A, the proximal synapse was at the soma (g<sub>M</sub> = 2*10<sup>−5</sup> µS), while the distal ...
<p><b><i>A,</i></b> Schematic proximal and distal ‘stimulating electrodes’ are shown activating one ...
<p>(<b>A-D</b>) EPSPs at different locations along a single dendritic branch (branch 3), as a respon...
<p>Trains (40 Hz) of inhibitory postsynaptic currents (IPSCs) at a synapse located at one of four po...
<p>(<b>A-C</b>) EPSP amplitude () as a function of distance from soma in 3 different branches (each ...
(A) Performance (i.e., maximal rate modulation, see Fig 2C; black curve) and energy costs (blue curv...
<p><b><i>A,</i></b> L3 model morphology <a href="http://www.ploscompbiol.org/article/info:doi/10.137...
<p>A, left, Depolarization vs. EPSC rate relation for inputs injected at the soma (•) and dendrite (...
<p>Simulation results with two excitatory inputs given at the location and . (A) The SC amplitude i...
<p>(A–D) Simulation results with the excitatory input given at the location and the inhibitory inpu...
<p>Shown are current traces associated with a model PN in response to direct current stimulation of ...
<p>A: Histogram showing EPSP amplitude distribution for N = 100 simulated neurons with 130 primary a...
1. Computer simulations were used to study the effect of voltage-dependent calcium and potassium con...
1. Computer simulations were used to study the effect of voltage-dependent calcium and potassium con...
<p>Electrotonic attenuation of the synaptic current along the dendrites en route to the soma, result...
<p>A, the proximal synapse was at the soma (g<sub>M</sub> = 2*10<sup>−5</sup> µS), while the distal ...
<p><b><i>A,</i></b> Schematic proximal and distal ‘stimulating electrodes’ are shown activating one ...
<p>(<b>A-D</b>) EPSPs at different locations along a single dendritic branch (branch 3), as a respon...
<p>Trains (40 Hz) of inhibitory postsynaptic currents (IPSCs) at a synapse located at one of four po...
<p>(<b>A-C</b>) EPSP amplitude () as a function of distance from soma in 3 different branches (each ...
(A) Performance (i.e., maximal rate modulation, see Fig 2C; black curve) and energy costs (blue curv...
<p><b><i>A,</i></b> L3 model morphology <a href="http://www.ploscompbiol.org/article/info:doi/10.137...
<p>A, left, Depolarization vs. EPSC rate relation for inputs injected at the soma (•) and dendrite (...
<p>Simulation results with two excitatory inputs given at the location and . (A) The SC amplitude i...
<p>(A–D) Simulation results with the excitatory input given at the location and the inhibitory inpu...
<p>Shown are current traces associated with a model PN in response to direct current stimulation of ...
<p>A: Histogram showing EPSP amplitude distribution for N = 100 simulated neurons with 130 primary a...
1. Computer simulations were used to study the effect of voltage-dependent calcium and potassium con...
1. Computer simulations were used to study the effect of voltage-dependent calcium and potassium con...