Anti-GITRLigand antibody treatment delays diabetes in CD28<sup>−/−</sup> NOD mice.
- Sylvaine You (369055)
- Lynn Poulton (369056)
- Steve Cobbold (369057)
- Chih-Pin Liu (284099)
- Michael Rosenzweig (369059)
- Douglas Ringler (369061)
- Wen-Hui Lee (272351)
- Berta Segovia (369064)
- Jean-François Bach (363467)
- Herman Waldmann (369067)
- Lucienne Chatenoud (369069)
Publication date
February 2013
DOIAbstract
<p>(A) Anti-GITRL antibody was administered into pre-diabetic 6-week-old CD28<sup>−/−</sup> NOD mice, 1 mg/injection/week for 4 consecutive weeks (n = 8). Diabetes development was significantly delayed as compared to the control group (p<0.023).</p
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