<p><i>Panel A</i>, Agarose gel of the PCR products from the experiment shown in the Table. <i>Panel B</i>, Extracted proteins were subjected to immunoblotting with an antibody against LRP4. <i>Panel C</i>, Protein extracts from primary osteoblast cultures after 6 days of in vitro differentiation were subjected to anti-LRP4 immunoblotting. Brain and calvarial extracts are shown as controls.</p
<p>(A) The relative absorbance of MC3T3-E1 cells transfected with a serial dilution of siLRP5 in the...
AbstractIn humans, low peak bone mass is a significant risk factor for osteoporosis. We report that ...
Skeletal health relies on architectural integrity and sufficient bone mass, which are maintained thr...
<p>Total RNA was extracted from embryonic brain (E18), calvaria and femur cortical bone of 10-week-o...
<p>(A) Lrp5 mRNA levels in primary calvarial osteoblasts were assessed by qPCR during 14 days of ost...
<p>(A) Lrp6 mRNA levels in primary calvarial osteoblasts were assessed by qPCR during 14 days of ost...
The human skeleton is affected by mutations in low-density lipoprotein receptor-related protein 5 (L...
Item does not contain fulltextIn humans, low peak bone mass is a significant risk factor for osteopo...
Abstract Humans lacking sclerostin display progressive bone overgrowth due to increased bone format...
Context: In states of health, bone mass is sustained in a coordinated effort by osteoblasts, osteocl...
<p>(A) Micrographs of human adipocytes. Human preadipocytes isolated from subcutaneous adipose tissu...
In humans, low peak bone mass is a significant risk factor for osteoporosis. We report that LRP5, en...
<p>A) Expression of <i>Lrp5</i> in WT and <i>Lrp5</i><sup><i>KO</i></sup> OBs. Expression values are...
<p>Representative microCT images from the proximal tibia (A) and femoral midshaft (B) are shown for ...
<p><i>Panel A</i>, Representative μCT images of WT and Lrp4ECD mouse femurs. <i>Panel B</i>, Total b...
<p>(A) The relative absorbance of MC3T3-E1 cells transfected with a serial dilution of siLRP5 in the...
AbstractIn humans, low peak bone mass is a significant risk factor for osteoporosis. We report that ...
Skeletal health relies on architectural integrity and sufficient bone mass, which are maintained thr...
<p>Total RNA was extracted from embryonic brain (E18), calvaria and femur cortical bone of 10-week-o...
<p>(A) Lrp5 mRNA levels in primary calvarial osteoblasts were assessed by qPCR during 14 days of ost...
<p>(A) Lrp6 mRNA levels in primary calvarial osteoblasts were assessed by qPCR during 14 days of ost...
The human skeleton is affected by mutations in low-density lipoprotein receptor-related protein 5 (L...
Item does not contain fulltextIn humans, low peak bone mass is a significant risk factor for osteopo...
Abstract Humans lacking sclerostin display progressive bone overgrowth due to increased bone format...
Context: In states of health, bone mass is sustained in a coordinated effort by osteoblasts, osteocl...
<p>(A) Micrographs of human adipocytes. Human preadipocytes isolated from subcutaneous adipose tissu...
In humans, low peak bone mass is a significant risk factor for osteoporosis. We report that LRP5, en...
<p>A) Expression of <i>Lrp5</i> in WT and <i>Lrp5</i><sup><i>KO</i></sup> OBs. Expression values are...
<p>Representative microCT images from the proximal tibia (A) and femoral midshaft (B) are shown for ...
<p><i>Panel A</i>, Representative μCT images of WT and Lrp4ECD mouse femurs. <i>Panel B</i>, Total b...
<p>(A) The relative absorbance of MC3T3-E1 cells transfected with a serial dilution of siLRP5 in the...
AbstractIn humans, low peak bone mass is a significant risk factor for osteoporosis. We report that ...
Skeletal health relies on architectural integrity and sufficient bone mass, which are maintained thr...