<p>Total RNA was extracted from embryonic brain (E18), calvaria and femur cortical bone of 10-week-old adult mice. Quantification of Lrp4 and control (36B4) mRNA was performed by real-time PCR. Results represent the average of cycle threshold (Ct)±S.D. in triplicate.</p
The human skeleton is affected by mutations in low-density lipoprotein receptor-related protein 5 (L...
<p>Column headings represent; WT = wild type mice, HYP = X-linked hypophosphatemic rickets mice,...
<p>(A) The relative absorbance of MC3T3-E1 cells transfected with a serial dilution of siLRP5 in the...
<p>(A) PCR analysis of Cre-mediated recombination of the Lrp5<sup>flox</sup> allele in ΔLrp5 mice. N...
<p>(A) PCR analysis of Cre-mediated recombination of the Lrp6<sup>flox</sup> allele in ΔLrp6 mice. (...
<p><i>Panel A</i>, Representative μCT images of WT and Lrp4ECD mouse femurs. <i>Panel B</i>, Total b...
<p><i>Panel A</i>, Agarose gel of the PCR products from the experiment shown in the Table. <i>Panel ...
<p>(A) Lrp5 mRNA levels in primary calvarial osteoblasts were assessed by qPCR during 14 days of ost...
<p><i>Panel A</i>, Representative μCT images of wild type and LRP4ECD mouse lumbar vertebra L3 and L...
<p>Representative microCT images from the proximal tibia (A) and femoral midshaft (B) are shown for ...
Wnt signaling plays a key role in regulating bone remodeling. In vitro studies suggest that scl...
<p>(A) Lrp6 mRNA levels in primary calvarial osteoblasts were assessed by qPCR during 14 days of ost...
Although Lrp5 is known to be an important contributor to the mechanisms regulating bone mass, its pr...
<p>(A) Real-time PCR analysis was performed using cDNA prepared from E10.5, E12.5 and E14.5 WT, HT a...
<p>Mice were sacrificed on day 28 and femurs collected for RNA purification as described in methods....
The human skeleton is affected by mutations in low-density lipoprotein receptor-related protein 5 (L...
<p>Column headings represent; WT = wild type mice, HYP = X-linked hypophosphatemic rickets mice,...
<p>(A) The relative absorbance of MC3T3-E1 cells transfected with a serial dilution of siLRP5 in the...
<p>(A) PCR analysis of Cre-mediated recombination of the Lrp5<sup>flox</sup> allele in ΔLrp5 mice. N...
<p>(A) PCR analysis of Cre-mediated recombination of the Lrp6<sup>flox</sup> allele in ΔLrp6 mice. (...
<p><i>Panel A</i>, Representative μCT images of WT and Lrp4ECD mouse femurs. <i>Panel B</i>, Total b...
<p><i>Panel A</i>, Agarose gel of the PCR products from the experiment shown in the Table. <i>Panel ...
<p>(A) Lrp5 mRNA levels in primary calvarial osteoblasts were assessed by qPCR during 14 days of ost...
<p><i>Panel A</i>, Representative μCT images of wild type and LRP4ECD mouse lumbar vertebra L3 and L...
<p>Representative microCT images from the proximal tibia (A) and femoral midshaft (B) are shown for ...
Wnt signaling plays a key role in regulating bone remodeling. In vitro studies suggest that scl...
<p>(A) Lrp6 mRNA levels in primary calvarial osteoblasts were assessed by qPCR during 14 days of ost...
Although Lrp5 is known to be an important contributor to the mechanisms regulating bone mass, its pr...
<p>(A) Real-time PCR analysis was performed using cDNA prepared from E10.5, E12.5 and E14.5 WT, HT a...
<p>Mice were sacrificed on day 28 and femurs collected for RNA purification as described in methods....
The human skeleton is affected by mutations in low-density lipoprotein receptor-related protein 5 (L...
<p>Column headings represent; WT = wild type mice, HYP = X-linked hypophosphatemic rickets mice,...
<p>(A) The relative absorbance of MC3T3-E1 cells transfected with a serial dilution of siLRP5 in the...
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