The methionine salvage pathway.

<p>The enzyme names are from <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000701#pgen.1000701-Sekowska2" target="_blank">[4]</a>, and compound names are from KEGG <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000701#pgen.1000701-Kanehisa1" target="_blank">[18]</a>. The reactions in black are known in bacteria <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000701#pgen.1000701-Sekowska2" target="_blank">[4]</a>. The yeast pathway is indicated by blue gene names under the corresponding enzymes <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000701#pgen.1000701-Pirkov1" target="_blank">[9]</a>. Dashed lines indicate variants of the pathway (see text). In <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000701#pgen.1000701-Ashida1" target="_blank">[5]</a> it was noted that the genes coding for mtnB and mtnC appear to be fused in <i>Arabidopsis thaliana</i>, and the genes for mtnB and mtnD appear to be fused in <i>Tetrahymena thermophila</i>, which indicates that the pathway in these organisms proceeds through the green and red reaction lines, respectively. We identified another fusion gene, between mtnK and mtnA, in <i>Tetrahymena</i> (red line).