CSN acts in neurons via Cullin1 or Cullin3.

<p>(A) PNS neurons in a non-mutant third instar larva, visualized by the <i>109(2)80-GAL4</i>-driven expression of <i>UAS-GFP</i>. (B) <i>CSN5</i> and <i>cullin1</i> interact genetically, simultaneous reduction of their functions represses dendritic development. (C) <i>CSN5</i> and <i>cullin3</i> interact genetically, <i>CSN5/cul3</i> double heterozygotes show increased dendritic elaboration. Single <i>CSN5, cullin1</i> or <i>cul3</i> heterozygous have no effect on dendritic development (not shown) (D) MARCM clone of a wild type ddaC neuron. (E) Loss of <i>cullin1</i> lead to decreased branching. (F) <i>cullin3</i>-mutant ddaC neurons demonstrate abnormal over-branching phenotype. Scale bar: 50 µm.